ID   YKGG_ECOLI              Reviewed;         231 AA.
AC   P77433; Q2MCB4;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   29-AUG-2001, sequence version 2.
DT   03-AUG-2022, entry version 122.
DE   RecName: Full=Uncharacterized protein YkgG;
GN   Name=ykgG; OrderedLocusNames=b0308, JW5042;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RA   Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA   Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA   Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT   "Sequence of minutes 4-25 of Escherichia coli.";
RL   Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   LACK OF COMPLEMENTATION OF B.SUBTILIS LUTABC OPERON.
RC   STRAIN=K12;
RX   PubMed=19201793; DOI=10.1128/jb.01464-08;
RA   Chai Y., Kolter R., Losick R.;
RT   "A widely conserved gene cluster required for lactate utilization in
RT   Bacillus subtilis and its involvement in biofilm formation.";
RL   J. Bacteriol. 191:2423-2430(2009).
CC   -!- MISCELLANEOUS: The E.coli ykgEFG operon is a clear homolog of the
CC       B.subtilis lutABC operon, however it is not able of restoring L-lactate
CC       utilization to the B.subtilis mutant for lutABC operon. Thus, ykgEFG
CC       operon may contribute to lactate catabolism in E.coli, but under
CC       conditions other than those tested, or alternatively, the ykgEFG operon
CC       may be responsible for the catabolism of a metabolite other than (but
CC       perhaps related to) lactate in E.coli.
CC   -!- SIMILARITY: Belongs to the LutC/YkgG family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB18035.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; U73857; AAB18035.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAC73411.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76092.1; -; Genomic_DNA.
DR   PIR; D64757; D64757.
DR   RefSeq; NP_414842.4; NC_000913.3.
DR   RefSeq; WP_000370307.1; NZ_SSZK01000067.1.
DR   AlphaFoldDB; P77433; -.
DR   SMR; P77433; -.
DR   BioGRID; 4261523; 4.
DR   STRING; 511145.b0308; -.
DR   jPOST; P77433; -.
DR   PaxDb; P77433; -.
DR   PRIDE; P77433; -.
DR   EnsemblBacteria; AAC73411; AAC73411; b0308.
DR   EnsemblBacteria; BAE76092; BAE76092; BAE76092.
DR   GeneID; 945906; -.
DR   KEGG; ecj:JW5042; -.
DR   KEGG; eco:b0308; -.
DR   PATRIC; fig|511145.12.peg.316; -.
DR   EchoBASE; EB3354; -.
DR   eggNOG; COG1556; Bacteria.
DR   HOGENOM; CLU_090664_1_0_6; -.
DR   InParanoid; P77433; -.
DR   OMA; PKTYIAI; -.
DR   PhylomeDB; P77433; -.
DR   BioCyc; EcoCyc:G6178-MON; -.
DR   PRO; PR:P77433; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005829; C:cytosol; IDA:EcoCyc.
DR   Gene3D; 3.40.50.10420; -; 1.
DR   InterPro; IPR024185; FTHF_cligase-like_sf.
DR   InterPro; IPR003741; LUD_dom.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   Pfam; PF02589; LUD_dom; 1.
DR   SUPFAM; SSF100950; SSF100950; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..231
FT                   /note="Uncharacterized protein YkgG"
FT                   /id="PRO_0000168570"
SQ   SEQUENCE   231 AA;  25213 MW;  8CE0331F1FE1A6DD CRC64;
     MDNRGEFLNN VAQALGRPLR LEPQAEDAPL NNYANERLTQ LNQQQRCDAF IQFASDVMLT
     RCELTSEAKA AEAAIRLCKE LGDQSVVISG DTRLEELGIS ERLQQECNAV VWDPAKGAEN
     ISQAEQAKVG VVYAEYGLTE SGGVVLFSAA ERGRSLSLLP EYSLFILRKS TILPRVAQLA
     EKLHQKAQAG ERMPSCINII SGPSSTADIE LIKVVGVHGP VKAVYLIIED C