YKHA_BACSU
ID YKHA_BACSU Reviewed; 172 AA.
AC P49851;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2004, sequence version 2.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Uncharacterized acyl-CoA thioester hydrolase YkhA;
DE EC=3.1.2.-;
GN Name=ykhA; OrderedLocusNames=BSU13030;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=8682784; DOI=10.1128/jb.178.13.3803-3808.1996;
RA Lacelle M., Kumano M., Kurita K., Yamane K., Zuber P., Nakano M.M.;
RT "Oxygen-controlled regulation of the flavohemoglobin gene in Bacillus
RT subtilis.";
RL J. Bacteriol. 178:3803-3808(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RA Devine K.M.;
RT "Sequence of the Bacillus subtilis genome between xlyA and ykoR.";
RL Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [4]
RP SEQUENCE REVISION.
RX PubMed=10568751; DOI=10.1101/gr.9.11.1116;
RA Medigue C., Rose M., Viari A., Danchin A.;
RT "Detecting and analyzing DNA sequencing errors: toward a higher quality of
RT the Bacillus subtilis genome sequence.";
RL Genome Res. 9:1116-1127(1999).
CC -!- SIMILARITY: Belongs to the acyl coenzyme A hydrolase family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA05583.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; D78189; BAA11257.1; -; Genomic_DNA.
DR EMBL; AJ002571; CAA05583.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL009126; CAB13160.2; -; Genomic_DNA.
DR PIR; E69856; E69856.
DR RefSeq; NP_389186.2; NC_000964.3.
DR RefSeq; WP_003244690.1; NZ_JNCM01000035.1.
DR AlphaFoldDB; P49851; -.
DR SMR; P49851; -.
DR STRING; 224308.BSU13030; -.
DR PaxDb; P49851; -.
DR PRIDE; P49851; -.
DR EnsemblBacteria; CAB13160; CAB13160; BSU_13030.
DR GeneID; 937988; -.
DR KEGG; bsu:BSU13030; -.
DR PATRIC; fig|224308.179.peg.1415; -.
DR eggNOG; COG1607; Bacteria.
DR InParanoid; P49851; -.
DR OMA; MDEMAFL; -.
DR PhylomeDB; P49851; -.
DR BioCyc; BSUB:BSU13030-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0047617; F:acyl-CoA hydrolase activity; IBA:GO_Central.
DR GO; GO:0036042; F:long-chain fatty acyl-CoA binding; IBA:GO_Central.
DR GO; GO:0006637; P:acyl-CoA metabolic process; IBA:GO_Central.
DR GO; GO:0006631; P:fatty acid metabolic process; IBA:GO_Central.
DR InterPro; IPR040170; Cytosol_ACT.
DR InterPro; IPR033120; HOTDOG_ACOT.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR006683; Thioestr_dom.
DR PANTHER; PTHR11049; PTHR11049; 1.
DR Pfam; PF03061; 4HBT; 1.
DR SUPFAM; SSF54637; SSF54637; 1.
DR PROSITE; PS51770; HOTDOG_ACOT; 1.
PE 3: Inferred from homology;
KW Hydrolase; Reference proteome.
FT CHAIN 1..172
FT /note="Uncharacterized acyl-CoA thioester hydrolase YkhA"
FT /id="PRO_0000053827"
FT DOMAIN 10..122
FT /note="HotDog ACOT-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01106"
FT REGION 148..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 172
FT /note="W -> WVNVKPKT (in Ref. 1; BAA11257)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 172 AA; 19298 MW; 2BBE2AFA2BADF4E6 CRC64;
METPETRFCK ESKVVKTSRV FPLDTNNHNT LFGGKLMSYI DDIASISAAR HCRRETVTAS
MDSVDFLKPI GQKDSVCLES YVTWVGTSSM EVFVKVIKEH LMTGERELAA TSFLTFVALD
SNGKPVPVPR VVPETEEEIM LHNTAVQRAN ERKNRKRHSQ ALANALGTDK PW
