ID   YKIC_SCHPO              Reviewed;         422 AA.
AC   Q9UUH0;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=Uncharacterized protein C630.12;
DE   Flags: Precursor;
GN   ORFNames=SPAC630.12;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC       {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329670; CAB52734.1; -; Genomic_DNA.
DR   PIR; T38990; T38990.
DR   RefSeq; NP_592908.1; NM_001018308.2.
DR   AlphaFoldDB; Q9UUH0; -.
DR   STRING; 4896.SPAC630.12.1; -.
DR   MaxQB; Q9UUH0; -.
DR   PaxDb; Q9UUH0; -.
DR   EnsemblFungi; SPAC630.12.1; SPAC630.12.1:pep; SPAC630.12.
DR   GeneID; 2543429; -.
DR   KEGG; spo:SPAC630.12; -.
DR   PomBase; SPAC630.12; -.
DR   VEuPathDB; FungiDB:SPAC630.12; -.
DR   eggNOG; KOG3662; Eukaryota.
DR   HOGENOM; CLU_011607_0_0_1; -.
DR   InParanoid; Q9UUH0; -.
DR   OMA; SRTLHCM; -.
DR   PhylomeDB; Q9UUH0; -.
DR   PRO; PR:Q9UUH0; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; ISO:PomBase.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; ISO:PomBase.
DR   CDD; cd08163; MPP_Cdc1; 1.
DR   Gene3D; 3.60.21.10; -; 1.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   InterPro; IPR041834; MPP_Cdc1.
DR   InterPro; IPR033308; PGAP5/Cdc1/Ted1.
DR   PANTHER; PTHR13315; PTHR13315; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   SUPFAM; SSF56300; SSF56300; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..422
FT                   /note="Uncharacterized protein C630.12"
FT                   /id="PRO_0000310852"
FT   TRANSMEM        339..359
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        402..422
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   422 AA;  49261 MW;  5688DB0FC81731FA CRC64;
     MKVGRFLVII AFCFYVLYLE KIIHTRPHKK CDWRSWEQWE STGNPVRIAL VADPQLVDDL
     TYDYPRPLIG IVKWISDQFL RRHWRYLHKS LKPDITFIMG DLMDTGREFA TEEFKKDYFR
     MMNVLDPKFT NKLEIYPGNH DIGFGNHAIV KDIQRFESLF GPTSRSIDVG NHTLVIVDGI
     RLSNNVNPQV YQPARDFLKS FETNKDNSRP RILLSHVPLF RPAINSCGEL REKDDVIKYG
     LGYQYQNLLL PELSESILKA VEPIAAFAGD DHDYCEVVHN YQVDTREAAT TEYNVKAFSM
     TSGILYPGYQ LLSLNYPYDN PKADQKSSYQ TKLCILPNQI QIYVWYGASI SIFFALILLR
     TAIFFFGTDR YSLPLYKTHA RRFSLSTTIH LFKKIVRITL STFISYTWIP FLLFIFLNIF
     II