ID   YKJ2_CAEEL              Reviewed;         323 AA.
AC   P34276; Q2L6Y8;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=GILT-like protein C02D5.2;
GN   ORFNames=C02D5.2;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=7906398; DOI=10.1038/368032a0;
RA   Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA   Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA   Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA   Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA   Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA   Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA   Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA   Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA   Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA   Wilkinson-Sproat J., Wohldman P.;
RT   "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT   elegans.";
RL   Nature 368:32-38(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=a;
CC         IsoId=P34276-1; Sequence=Displayed;
CC       Name=b;
CC         IsoId=P34276-2; Sequence=VSP_020781;
CC   -!- SIMILARITY: Belongs to the GILT family. {ECO:0000305}.
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DR   EMBL; FO080279; CCD62558.1; -; Genomic_DNA.
DR   EMBL; FO080279; CCD62559.1; -; Genomic_DNA.
DR   PIR; S44744; S44744.
DR   RefSeq; NP_001040839.1; NM_001047374.2. [P34276-1]
DR   RefSeq; NP_001040840.1; NM_001047375.1. [P34276-2]
DR   AlphaFoldDB; P34276; -.
DR   SMR; P34276; -.
DR   EPD; P34276; -.
DR   PaxDb; P34276; -.
DR   PeptideAtlas; P34276; -.
DR   EnsemblMetazoa; C02D5.2a.1; C02D5.2a.1; WBGene00015336. [P34276-1]
DR   EnsemblMetazoa; C02D5.2b.1; C02D5.2b.1; WBGene00015336. [P34276-2]
DR   GeneID; 176203; -.
DR   KEGG; cel:CELE_C02D5.2; -.
DR   UCSC; C02D5.2a; c. elegans. [P34276-1]
DR   CTD; 176203; -.
DR   WormBase; C02D5.2a; CE00034; WBGene00015336; -. [P34276-1]
DR   WormBase; C02D5.2b; CE39554; WBGene00015336; -. [P34276-2]
DR   eggNOG; KOG3160; Eukaryota.
DR   GeneTree; ENSGT00390000010450; -.
DR   HOGENOM; CLU_066886_2_0_1; -.
DR   InParanoid; P34276; -.
DR   OMA; DFIPWIV; -.
DR   OrthoDB; 803513at2759; -.
DR   PhylomeDB; P34276; -.
DR   Reactome; R-CEL-2132295; MHC class II antigen presentation.
DR   PRO; PR:P34276; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00015336; Expressed in pharyngeal muscle cell (C elegans) and 3 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR   GO; GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IEA:InterPro.
DR   InterPro; IPR004911; Interferon-induced_GILT.
DR   PANTHER; PTHR13234; PTHR13234; 1.
DR   Pfam; PF03227; GILT; 1.
PE   3: Inferred from homology;
KW   Alternative splicing; Glycoprotein; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..323
FT                   /note="GILT-like protein C02D5.2"
FT                   /id="PRO_0000065106"
FT   TRANSMEM        13..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        37..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        87..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        35
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        289
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   VAR_SEQ         1..60
FT                   /note="Missing (in isoform b)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_020781"
SQ   SEQUENCE   323 AA;  36932 MW;  DC5F79CEF32B01C8 CRC64;
     MSKYLRTSHP SPLICRPILT FSSLHILTAF LISGNSSYIN WSVTIILLIL GLYACHRFLN
     MKKLTRDAQE PLLPHIRPST RNKIRKYIYG TIFILSIFLL YRSLNSPDTS KHGIGRNGDF
     IEYEPKAGPT IKEPVENIVK LDVYMEAQCP DTSRFFRQQL KKAWDILGRL NRIELNVIPF
     GKARCTEKGN DFECQCQHGP TECQINQLMN CVIDRFGFPH RYLPGVLCMQ GKYSLDEAMK
     CVTENYPSEY ERMRECASGT RGRRLLALSG QKTASLTPAI DFIPWIVING SRNSDALYDL
     TQNVCEAMQP MPSACKDYLR SLQ