ID   YKK3_CAEEL              Reviewed;         366 AA.
AC   P34280;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2004, sequence version 2.
DT   03-AUG-2022, entry version 136.
DE   RecName: Full=Uncharacterized GTP-binding protein C02F5.3;
GN   ORFNames=C02F5.3;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=7906398; DOI=10.1038/368032a0;
RA   Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA   Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA   Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA   Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA   Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA   Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA   Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA   Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA   Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA   Wilkinson-Sproat J., Wohldman P.;
RT   "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT   elegans.";
RL   Nature 368:32-38(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SIMILARITY: Belongs to the TRAFAC class OBG-HflX-like GTPase
CC       superfamily. OBG GTPase family. {ECO:0000255|PROSITE-ProRule:PRU01047}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FO080288; CCD62627.1; -; Genomic_DNA.
DR   PIR; S44605; S44605.
DR   RefSeq; NP_498808.2; NM_066407.5.
DR   AlphaFoldDB; P34280; -.
DR   SMR; P34280; -.
DR   BioGRID; 41367; 4.
DR   STRING; 6239.C02F5.3; -.
DR   EPD; P34280; -.
DR   PaxDb; P34280; -.
DR   PeptideAtlas; P34280; -.
DR   EnsemblMetazoa; C02F5.3.1; C02F5.3.1; WBGene00015346.
DR   GeneID; 176163; -.
DR   KEGG; cel:CELE_C02F5.3; -.
DR   UCSC; C02F5.3; c. elegans.
DR   CTD; 176163; -.
DR   WormBase; C02F5.3; CE36094; WBGene00015346; -.
DR   eggNOG; KOG1486; Eukaryota.
DR   GeneTree; ENSGT00940000153340; -.
DR   HOGENOM; CLU_044997_0_0_1; -.
DR   InParanoid; P34280; -.
DR   OMA; VCDQVHR; -.
DR   OrthoDB; 754662at2759; -.
DR   PhylomeDB; P34280; -.
DR   PRO; PR:P34280; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00015346; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005525; F:GTP binding; IBA:GO_Central.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR   CDD; cd01896; DRG; 1.
DR   Gene3D; 3.10.20.30; -; 1.
DR   InterPro; IPR012675; Beta-grasp_dom_sf.
DR   InterPro; IPR045001; DRG.
DR   InterPro; IPR031167; G_OBG.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR031662; GTP-binding_2.
DR   InterPro; IPR006074; GTP1-OBG_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR004095; TGS.
DR   InterPro; IPR012676; TGS-like.
DR   PANTHER; PTHR43127; PTHR43127; 1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   Pfam; PF16897; MMR_HSR1_Xtn; 1.
DR   Pfam; PF02824; TGS; 1.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF81271; SSF81271; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51710; G_OBG; 1.
DR   PROSITE; PS00905; GTP1_OBG; 1.
DR   PROSITE; PS51880; TGS; 1.
PE   3: Inferred from homology;
KW   GTP-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..366
FT                   /note="Uncharacterized GTP-binding protein C02F5.3"
FT                   /id="PRO_0000205451"
FT   DOMAIN          63..288
FT                   /note="OBG-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
FT   DOMAIN          288..365
FT                   /note="TGS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01228"
FT   BINDING         69..76
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
FT   BINDING         115..119
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
FT   BINDING         246..249
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
SQ   SEQUENCE   366 AA;  40822 MW;  0C9EFCBA1D40DBEC CRC64;
     MGILEKIAEI EHEISRTQKN KATEYHLGLL KAKLAKYRQQ LLEPTGKGGA KGEGFDVMKS
     GDARVAMVGF PSVGKSTLLS SMTSTHSEAA GYEFTTLTCI PGVISYNGAN IQLLDLPGII
     EGASQGKGRG RQVISVAKTA DLILMMLDAG KSDQQKMLLE RELEAVGIRL NKKPPNIYVK
     QKKVGGVKFT NTVPLTHCNE KLIMTVLHEY KIFNADVIFR EDCTVDEFID VIQGNRVYMT
     CLYVYNKVDQ ISIEEIDRLA RMPHHVVISC EMNLNMDYLL EKMWEYLALV RVYTKKPGNA
     PDLGPEDGII LRGGATIEHC CHALHRSIAA QLRYAIVWGT STKFSPQRVG LHHKLDHEDV
     IQIVKK