ID   YKK7_YEAST              Reviewed;         309 AA.
AC   P34251; D6VXI0;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 150.
DE   RecName: Full=Uncharacterized oxidoreductase YKL107W;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=YKL107W; ORFNames=YKL462;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=8109175; DOI=10.1002/yea.320091113;
RA   Cheret G., Pallier C., Valens M., Daignan-Fornier B., Fukuhara H.,
RA   Bolotin-Fukuhara M., Sor F.;
RT   "The DNA sequence analysis of the HAP4-LAP4 region on chromosome XI of
RT   Saccharomyces cerevisiae suggests the presence of a second aspartate
RT   aminotransferase gene in yeast.";
RL   Yeast 9:1259-1265(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=8196765; DOI=10.1038/369371a0;
RA   Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V.,
RA   Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P.,
RA   Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L.,
RA   Daignan-Fornier B., del Rey F., Dion C., Domdey H., Duesterhoeft A.,
RA   Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H.,
RA   Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L.,
RA   Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M.,
RA   Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H.,
RA   Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J.,
RA   Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H.,
RA   Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J.,
RA   Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S.,
RA   Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F.,
RA   Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R.,
RA   Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W.,
RA   Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M.,
RA   Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C.,
RA   Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H.,
RA   Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L.,
RA   van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S.,
RA   von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M.,
RA   Becker I., Mewes H.-W.;
RT   "Complete DNA sequence of yeast chromosome XI.";
RL   Nature 369:371-378(1994).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the NmrA-type oxidoreductase family.
CC       {ECO:0000305}.
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DR   EMBL; X71133; CAA50450.1; -; Genomic_DNA.
DR   EMBL; Z28107; CAA81947.1; -; Genomic_DNA.
DR   EMBL; BK006944; DAA09050.1; -; Genomic_DNA.
DR   PIR; S37934; S37934.
DR   RefSeq; NP_012815.1; NM_001179673.1.
DR   AlphaFoldDB; P34251; -.
DR   SMR; P34251; -.
DR   BioGRID; 34026; 24.
DR   DIP; DIP-4754N; -.
DR   STRING; 4932.YKL107W; -.
DR   PaxDb; P34251; -.
DR   PRIDE; P34251; -.
DR   EnsemblFungi; YKL107W_mRNA; YKL107W; YKL107W.
DR   GeneID; 853753; -.
DR   KEGG; sce:YKL107W; -.
DR   SGD; S000001590; YKL107W.
DR   VEuPathDB; FungiDB:YKL107W; -.
DR   eggNOG; KOG1208; Eukaryota.
DR   HOGENOM; CLU_082210_0_0_1; -.
DR   InParanoid; P34251; -.
DR   OMA; AHMNTVA; -.
DR   BioCyc; YEAST:G3O-31893-MON; -.
DR   Reactome; R-SCE-5365859; RA biosynthesis pathway.
DR   PRO; PR:P34251; -.
DR   Proteomes; UP000002311; Chromosome XI.
DR   RNAct; P34251; protein.
DR   GO; GO:0005783; C:endoplasmic reticulum; IDA:SGD.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IDA:SGD.
DR   GO; GO:1901426; P:response to furfural; IMP:SGD.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Membrane; Oxidoreductase; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..309
FT                   /note="Uncharacterized oxidoreductase YKL107W"
FT                   /id="PRO_0000203158"
FT   TRANSMEM        23..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   309 AA;  34524 MW;  DD3F5A1F9526ACD3 CRC64;
     MFWKKDPTVS WERKNINDID FSRFNVAIIG GTGGLGRAIS RELAQRNARV TVVGQTFRDE
     DLKDKINFVK ADLSLVSECK RISHSDEIPY EELTHLIFTT GIFASRQRQA TSEGLEKDMA
     VSYLSRYIIF HDVAKRLGIS RTKKDDLPKV FIAGFPGNGQ VGDPDDLNSD EKKYSAYATH
     MNTVAANESL VIDAKDRYTN IDTFGLNPGL IKTNIRNNLL GSDTYLSRIT EWIISWTCQS
     AETYAKTICT LIASPAIESR SGTMFSNKGD AILPSPGLTK DVVEKFMENS ELLVEKALRN
     QSPFTSSNE