YKNW_BACSU
ID YKNW_BACSU Reviewed; 231 AA.
AC O31709;
DT 26-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Membrane protein YknW {ECO:0000305};
GN Name=yknW; OrderedLocusNames=BSU14340 {ECO:0000312|EMBL:CAB13307.1};
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RA Caldwell R.M., Ferrari E.;
RT "Sequence analysis of the mobA-ampS region of the Bacillus subtilis
RT chromosome.";
RL Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP FUNCTION, SUBUNIT, SUBCELLULAR LOCATION, AND INDUCTION.
RC STRAIN=168;
RX PubMed=22707703; DOI=10.1128/jb.00223-12;
RA Yamada Y., Tikhonova E.B., Zgurskaya H.I.;
RT "YknWXYZ is an unusual four-component transporter with a role in protection
RT against sporulation-delaying-protein-induced killing of Bacillus
RT subtilis.";
RL J. Bacteriol. 194:4386-4394(2012).
CC -!- FUNCTION: Part of an unusual four-component transporter, which is
CC required for protection against the killing factor SdpC (sporulation-
CC delaying protein). Has a role in the assembly of the YknXYZ complex.
CC {ECO:0000269|PubMed:22707703}.
CC -!- SUBUNIT: Interacts with a complex composed of YknX, YknY and YknZ.
CC {ECO:0000269|PubMed:22707703}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:22707703};
CC Multi-pass membrane protein {ECO:0000255}.
CC -!- INDUCTION: Expressed in exponential-phase cells.
CC {ECO:0000269|PubMed:22707703}.
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DR EMBL; AF012285; AAC24908.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB13307.1; -; Genomic_DNA.
DR PIR; B69858; B69858.
DR RefSeq; NP_389317.1; NC_000964.3.
DR RefSeq; WP_003232360.1; NZ_JNCM01000035.1.
DR AlphaFoldDB; O31709; -.
DR STRING; 224308.BSU14340; -.
DR TCDB; 9.B.29.2.17; the 4-5 tms putative chaperone (4-5pc) family.
DR jPOST; O31709; -.
DR PaxDb; O31709; -.
DR PRIDE; O31709; -.
DR EnsemblBacteria; CAB13307; CAB13307; BSU_14340.
DR GeneID; 938771; -.
DR KEGG; bsu:BSU14340; -.
DR PATRIC; fig|224308.179.peg.1564; -.
DR eggNOG; ENOG5033CY2; Bacteria.
DR OMA; IYWLCVK; -.
DR BioCyc; BSUB:BSU14340-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR006977; Yip1_dom.
DR Pfam; PF04893; Yip1; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..231
FT /note="Membrane protein YknW"
FT /id="PRO_0000049605"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 205..225
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 231 AA; 24175 MW; 352549910153A630 CRC64;
METNVEKNSG TATEKPSLFG VITSPSVQFE RIRERPAVWG PLLIVAAIII VGAVLQSLGT
DYSELLKSQD TQGLSAEQME TVATITKFGG MAGAIIGGIA ALFIAPLIYW LCVKVSGGVT
TYKKMLSLSL FVSLISSLGL LVNGIVAFTT DVNPLYSTTS LAGIIPSDGA LASVLNTFEI
FSIWSFVLLA IGLHKTGGIS KKAGWISAII LFGILVVFSL FSGLINSVAG A
