ID   YKP5_KLULA              Reviewed;         158 AA.
AC   P05471;
DT   01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1988, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Uncharacterized killer plasmid pGKl-2 protein 5;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OG   Plasmid pGKl-2.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=3041369; DOI=10.1093/nar/16.13.5863;
RA   Tommasino M., Ricci S., Galeotti C.L.;
RT   "Genome organization of the killer plasmid pGKL2 from Kluyveromyces
RT   lactis.";
RL   Nucleic Acids Res. 16:5863-5878(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=3138657;
RA   Wilson D.W., Meacock P.A.;
RT   "Extranuclear gene expression in yeast: evidence for a plasmid-encoded RNA
RT   polymerase of unique structure.";
RL   Nucleic Acids Res. 16:8097-8112(1988).
CC   -!- FUNCTION: The presence of the two linear plasmids, termed pGKL1 and
CC       pGKL2, in strains of Kluyveromyces lactis confers the killer phenotype
CC       to the host cell, by promoting the secretion of a toxin able to inhibit
CC       the growth of sensitive strains.
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DR   EMBL; X07776; CAA30606.1; -; Genomic_DNA.
DR   EMBL; X07946; CAA30771.1; -; Genomic_DNA.
DR   PIR; S00963; S00963.
DR   AlphaFoldDB; P05471; -.
DR   Proteomes; UP000000598; Plasmid pGKL2.
DR   InterPro; IPR035145; DUF5482.
DR   Pfam; PF17579; DUF5482; 1.
PE   4: Predicted;
KW   Plasmid; Reference proteome.
FT   CHAIN           1..158
FT                   /note="Uncharacterized killer plasmid pGKl-2 protein 5"
FT                   /id="PRO_0000066279"
SQ   SEQUENCE   158 AA;  18094 MW;  9DCDC2B58291E34D CRC64;
     MIYDKIDTKL IKLGKTNKFS GEEEKSITSL YYEDESFEFS FKNKYVKITK IETNAYGKKF
     VTIKSKLYAD IVEKVAKELD AVSPILSDGS FRATINDATS FSKDVGEYSF YACVSLYFPS
     IYKDTEKTTL QVYLKEVVVT KIIKNNLEVE FDKLSLAI