CBIN_SALEP
ID CBIN_SALEP Reviewed; 93 AA.
AC B5QYX9;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 04-NOV-2008, sequence version 1.
DT 25-MAY-2022, entry version 63.
DE RecName: Full=Cobalt transport protein CbiN {ECO:0000255|HAMAP-Rule:MF_00330};
DE AltName: Full=Energy-coupling factor transporter probable substrate-capture protein CbiN {ECO:0000255|HAMAP-Rule:MF_00330};
DE Short=ECF transporter S component CbiN {ECO:0000255|HAMAP-Rule:MF_00330};
GN Name=cbiN {ECO:0000255|HAMAP-Rule:MF_00330}; OrderedLocusNames=SEN2020;
OS Salmonella enteritidis PT4 (strain P125109).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=550537;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P125109;
RX PubMed=18583645; DOI=10.1101/gr.077404.108;
RA Thomson N.R., Clayton D.J., Windhorst D., Vernikos G., Davidson S.,
RA Churcher C., Quail M.A., Stevens M., Jones M.A., Watson M., Barron A.,
RA Layton A., Pickard D., Kingsley R.A., Bignell A., Clark L., Harris B.,
RA Ormond D., Abdellah Z., Brooks K., Cherevach I., Chillingworth T.,
RA Woodward J., Norberczak H., Lord A., Arrowsmith C., Jagels K., Moule S.,
RA Mungall K., Saunders M., Whitehead S., Chabalgoity J.A., Maskell D.,
RA Humphreys T., Roberts M., Barrow P.A., Dougan G., Parkhill J.;
RT "Comparative genome analysis of Salmonella enteritidis PT4 and Salmonella
RT gallinarum 287/91 provides insights into evolutionary and host adaptation
RT pathways.";
RL Genome Res. 18:1624-1637(2008).
CC -!- FUNCTION: Part of the energy-coupling factor (ECF) transporter complex
CC CbiMNOQ involved in cobalt import. {ECO:0000255|HAMAP-Rule:MF_00330}.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00330}.
CC -!- SUBUNIT: Forms an energy-coupling factor (ECF) transporter complex
CC composed of an ATP-binding protein (A component, CbiO), a transmembrane
CC protein (T component, CbiQ) and 2 possible substrate-capture proteins
CC (S components, CbiM and CbiN) of unknown stoichimetry.
CC {ECO:0000255|HAMAP-Rule:MF_00330}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00330}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_00330}.
CC -!- SIMILARITY: Belongs to the CbiN family. {ECO:0000255|HAMAP-
CC Rule:MF_00330}.
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DR EMBL; AM933172; CAR33600.1; -; Genomic_DNA.
DR RefSeq; WP_000753212.1; NC_011294.1.
DR AlphaFoldDB; B5QYX9; -.
DR KEGG; set:SEN2020; -.
DR HOGENOM; CLU_136197_2_0_6; -.
DR OMA; TEIEPDY; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000000613; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR HAMAP; MF_00330; CbiN; 1.
DR InterPro; IPR003705; CbiN.
DR PANTHER; PTHR38662; PTHR38662; 1.
DR Pfam; PF02553; CbiN; 1.
DR TIGRFAMs; TIGR01165; cbiN; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Cobalamin biosynthesis; Cobalt;
KW Cobalt transport; Ion transport; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..93
FT /note="Cobalt transport protein CbiN"
FT /id="PRO_1000116111"
FT TRANSMEM 5..25
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00330"
FT TRANSMEM 63..83
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00330"
SQ SEQUENCE 93 AA; 10269 MW; CA39465DECCA648A CRC64;
MKKTLMLLAM VVALVILPFF INHGGEYGGS DGEAESQIQA IAPQYKPWFQ PLYEPASGEI
ESLLFTLQGS LGAAVIFYIL GYCKGKQRRD DRA
