ID   YKR1_CAEEL              Reviewed;         886 AA.
AC   P34307;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   06-JUN-2002, sequence version 2.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=KH domain-containing protein C06G4.1;
GN   ORFNames=C06G4.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=7906398; DOI=10.1038/368032a0;
RA   Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA   Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA   Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA   Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA   Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA   Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA   Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA   Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA   Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA   Wilkinson-Sproat J., Wohldman P.;
RT   "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT   elegans.";
RL   Nature 368:32-38(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FO080399; CCD63431.1; -; Genomic_DNA.
DR   PIR; S44748; S44748.
DR   RefSeq; NP_498742.1; NM_066341.3.
DR   AlphaFoldDB; P34307; -.
DR   SMR; P34307; -.
DR   BioGRID; 41329; 2.
DR   IntAct; P34307; 1.
DR   STRING; 6239.C06G4.1; -.
DR   EPD; P34307; -.
DR   PaxDb; P34307; -.
DR   PeptideAtlas; P34307; -.
DR   PRIDE; P34307; -.
DR   EnsemblMetazoa; C06G4.1.1; C06G4.1.1; WBGene00015557.
DR   GeneID; 176123; -.
DR   KEGG; cel:CELE_C06G4.1; -.
DR   UCSC; C06G4.1; c. elegans.
DR   CTD; 176123; -.
DR   WormBase; C06G4.1; CE28203; WBGene00015557; -.
DR   eggNOG; KOG2208; Eukaryota.
DR   HOGENOM; CLU_325481_0_0_1; -.
DR   InParanoid; P34307; -.
DR   OrthoDB; 971207at2759; -.
DR   PRO; PR:P34307; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00015557; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR   GO; GO:0048024; P:regulation of mRNA splicing, via spliceosome; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   Gene3D; 3.30.1370.10; -; 2.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   Pfam; PF00013; KH_1; 2.
DR   SMART; SM00322; KH; 3.
DR   SUPFAM; SSF54791; SSF54791; 2.
DR   PROSITE; PS50084; KH_TYPE_1; 2.
PE   4: Predicted;
KW   Reference proteome; Repeat; RNA-binding.
FT   CHAIN           1..886
FT                   /note="KH domain-containing protein C06G4.1"
FT                   /id="PRO_0000050162"
FT   DOMAIN          698..761
FT                   /note="KH 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT   DOMAIN          775..839
FT                   /note="KH 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT   REGION          359..433
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        368..386
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        387..414
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   886 AA;  103580 MW;  EA8EA91BB3AACD29 CRC64;
     MAKTKDKSIF VSSVDSDSDI EEIIMPPKPP VEVIQLDDSD DECQDICKPI YNKKVHKDPI
     VRVSYRQRIP ESYFPGISTS LINVQREHNN RSKYDTWGSN SCSEPRISIS NIERLEKPSY
     HEARRVPVFE RLERSREISN GRNNQNPIRF NHKFVPPINR QTPLFNNQQL LVNVPFNEHH
     PTFLEPRPFY RSNVNEYNAG GLNRGSFRKM GRLNMEIVRD NDDFEEHFLA PNFPAKSASI
     DRRVDDSLSS NSYLRSGMIM ASSERLEDPR FSGRLPVFAR QINNQEINND NFYQNSICYN
     HNNYPSNLES RVSFPFEARH HDADGLNRGR YQVMEHVNMG IMRNSEDFED YDITQTDQDN
     HFYNDKDSGK HHRHRHRSKN NKKHKKHYDR NESGNSSECR EEDDYEISNP SEKRHERKKR
     QRSSHRKESA CVDEDNYILD EDRFYQQESD EYHNSLEMER EYEHGMDVGV KKEHSYKCDD
     IARNARKRAR LTDDDMARRE ELFKEWSYSK EIVDGVTQLF GGPPRESERH QKKQKELVFE
     ADRTAMHALS IRSGALVKAR LLEIHYATGC HLIFLEEVKR GGYTYVELKG DPEHIKNAQK
     MIDDMVIDEH YIHDGRESIV YFYNAPHELR NTRGFDLNCR SIEKYCGIII EKMREVFGIG
     GYVSTAPLKL TGSVNSIHMA RETMQSKTKR FLDEEKFKET VEHCTPISFY RKIIGRCGEN
     LKTIEKVTRT AIVFKRSFDN NEACFSIRGR TDNIKQAIEK IEEITHENQP ADDDPGIFQV
     RVPENMVARL IGRHGVEINR IRSESKAKCY LNAIRGNLDD KFMVCSGGVE EAAYAAYLTK
     VKIGIIDPKV IQFNSDDFNN LSKVKPMEDP RLVMLKKRYA ERKECK