YKR5_CAEEL
ID YKR5_CAEEL Reviewed; 436 AA.
AC P34311;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 10-JAN-2006, sequence version 3.
DT 03-AUG-2022, entry version 142.
DE RecName: Full=Probable G-protein coupled receptor C06G4.5;
GN ORFNames=C06G4.5;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=7906398; DOI=10.1038/368032a0;
RA Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA Wilkinson-Sproat J., Wohldman P.;
RT "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT elegans.";
RL Nature 368:32-38(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Putative receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; FO080399; CCD63437.1; -; Genomic_DNA.
DR PIR; S44747; S44747.
DR RefSeq; NP_498743.2; NM_066342.4.
DR AlphaFoldDB; P34311; -.
DR SMR; P34311; -.
DR STRING; 6239.C06G4.5; -.
DR EPD; P34311; -.
DR PaxDb; P34311; -.
DR EnsemblMetazoa; C06G4.5.1; C06G4.5.1; WBGene00015559.
DR GeneID; 176124; -.
DR KEGG; cel:CELE_C06G4.5; -.
DR UCSC; C06G4.5; c. elegans.
DR CTD; 176124; -.
DR WormBase; C06G4.5; CE38997; WBGene00015559; npr-17.
DR eggNOG; KOG3656; Eukaryota.
DR GeneTree; ENSGT01030000234534; -.
DR HOGENOM; CLU_048644_0_0_1; -.
DR InParanoid; P34311; -.
DR OMA; WSFTARE; -.
DR OrthoDB; 1011272at2759; -.
DR PhylomeDB; P34311; -.
DR Reactome; R-CEL-202040; G-protein activation.
DR Reactome; R-CEL-391908; Prostanoid ligand receptors.
DR Reactome; R-CEL-416476; G alpha (q) signalling events.
DR Reactome; R-CEL-418594; G alpha (i) signalling events.
DR Reactome; R-CEL-5620922; BBSome-mediated cargo-targeting to cilium.
DR PRO; PR:P34311; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00015559; Expressed in adult organism and 3 other tissues.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0043005; C:neuron projection; IBA:GO_Central.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IBA:GO_Central.
DR GO; GO:0042277; F:peptide binding; IBA:GO_Central.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; G-protein coupled receptor; Glycoprotein; Membrane;
KW Receptor; Reference proteome; Transducer; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..436
FT /note="Probable G-protein coupled receptor C06G4.5"
FT /id="PRO_0000070224"
FT TOPO_DOM 1..53
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 54..74
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 75..94
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 95..115
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 116..132
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 133..153
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 154..171
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 193..230
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 231..251
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 252..281
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 282..302
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 303..316
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 317..337
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 338..436
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 15
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 309
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 436 AA; 49167 MW; 0224D0024B0F8894 CRC64;
MSTNLVDYVD DSYLNQSMNS ENGLDSVTQI MYDMKKYNIV NDVLPPPNHE DLHVVIMAVS
YLLLFLLGTC GNVAVLTTIY HVIRSSRATL DNTLIYVIVL SCVDFGVCLS LPITVIDQIL
GFWMFGKIPC KLHAVFENFG KILSALILTA MSFDRYAGVC HPQRKRLRSR NFAITILLVL
AVYAFITLCP LLWSFTAREI ILYAKETAPG MLTRMKIEKC TVDIDSQMFT AFTIYQFILC
YCTPLVLIAF FYTKLLSKLR EHTRTFKSSQ IPFLHISLYT LAVACFYFLC WTPFWMATLF
AVYLENSANS SSVPPVFVYI MYFIHALPFT NSAINWILYG ALNGQLQQRY RSNRSNSTKK
TTTTTASTAL LEKKITNLNT NSNYQVNGSM NSIATAAPTK TIGNNEVLVA TSTIDDDVAT
DVVDVRLLSN HNPTFL
