YKT4_SCHPO
ID YKT4_SCHPO Reviewed; 1236 AA.
AC Q9C105;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 117.
DE RecName: Full=Chitinase-like protein PB1E7.04c;
DE EC=3.2.1.-;
DE Flags: Precursor;
GN ORFNames=SPAPB1E7.04c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. Chitinase
CC class III subfamily. {ECO:0000305}.
CC -!- CAUTION: Lacks the conserved Glu residue in position 166 essential for
CC chitinase activity. Its enzyme activity is therefore unsure.
CC {ECO:0000305}.
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DR EMBL; CU329670; CAC36921.1; -; Genomic_DNA.
DR RefSeq; NP_594130.1; NM_001019554.2.
DR AlphaFoldDB; Q9C105; -.
DR SMR; Q9C105; -.
DR BioGRID; 280097; 29.
DR STRING; 4896.SPAPB1E7.04c.1; -.
DR CAZy; GH18; Glycoside Hydrolase Family 18.
DR iPTMnet; Q9C105; -.
DR MaxQB; Q9C105; -.
DR PaxDb; Q9C105; -.
DR EnsemblFungi; SPAPB1E7.04c.1; SPAPB1E7.04c.1:pep; SPAPB1E7.04c.
DR GeneID; 2543683; -.
DR KEGG; spo:SPAPB1E7.04c; -.
DR PomBase; SPAPB1E7.04c; -.
DR VEuPathDB; FungiDB:SPAPB1E7.04c; -.
DR eggNOG; KOG4701; Eukaryota.
DR HOGENOM; CLU_267181_0_0_1; -.
DR InParanoid; Q9C105; -.
DR OMA; NIGQINW; -.
DR PRO; PR:Q9C105; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005576; C:extracellular region; IBA:GO_Central.
DR GO; GO:0009277; C:fungal-type cell wall; ISO:PomBase.
DR GO; GO:0000324; C:fungal-type vacuole; HDA:PomBase.
DR GO; GO:0004568; F:chitinase activity; ISO:PomBase.
DR GO; GO:0034232; P:ascospore wall chitin catabolic process; IC:PomBase.
DR CDD; cd02877; GH18_hevamine_XipI_class_III; 1.
DR InterPro; IPR045321; Cts1-like.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR SUPFAM; SSF51445; SSF51445; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Glycosidase; Hydrolase; Reference proteome; Secreted; Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..1236
FT /note="Chitinase-like protein PB1E7.04c"
FT /id="PRO_0000314114"
FT DOMAIN 26..325
FT /note="GH18"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01258"
FT REGION 326..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 584..625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 804..836
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 868..927
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 946..979
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1125..1159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 333..367
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 21
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 24
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 54
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 123
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 225
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 237
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 255
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 267
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 277
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 288
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 309
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 715
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 737
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 768
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 786
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 813
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 1236 AA; 123388 MW; 5A2D33A30B87CDD8 CRC64;
MRLISSLLLL VYSARLALSL NLTNQTAVLG YWGSNLAGKM GDRDQKRLSS YCQNTTYDAI
ILSSVIDFNV DGWPVYDFSN LCSDSDTFSG SELKKCPQIE TDIQVCQENG IKVLLSIGGY
NGNFSLNNDD DGTNFAFQVW NIFGSGEDSY RPFGKAVVDG FDLEVNKGTN TAYSAFAKRM
LEIYASDPRR KYYISAAPTC MVPDHTLTKA ISENSFDFLS IHTFNSSTGE GCSGSRNSTF
DAWVEYAEDS AYNTNTSLFY GVVGHQNGSN GFISPKNLTR DLLNYKANST LFGGVTIWDT
SLAAMSYDNS SETFVEAIHK ILDTKSKHSS SKSSHDSSQG LESTSSIALN PTSSISSTSS
SSSTSSAIST ISQDHTKTVT SVSDEPTTIT ASGATSVTTT TKTDFDTVTT TIVSTSTLIS
ASDSTSIIVS SYVSTVTQPA STRVQTTTVS SISTSVKQPT ASVASSSVSV PSSSSVQPQS
STPISSSSSA SSPQSTLSTS SEVVSEVSST LLSGSSAIPS TSSSTPSSSI ISSPMTSVLS
SSSSIPTSSS SDFSSSITTI SSGISSSSIP STFSSVSSIL SSSTSSPSST SLSISSSSTS
STFSSASTSS PSSISSSISS SSTILSSPTP STSSLMISSS SIISGSSSIL SSSISTIPIS
SSLSTYSSSV IPSSSTLVSS SSSLIVSSSP VASSSSSPIP SSSSLVSTYS ASLSNITHSS
LSLTAMSSSS AIPTSVNSST LITASSSNTL LSSITSSSAI VSSTTVSNIS SNLPSATASS
QSQLTNSSTL ATSLYLSSSS SRTISTSSTN EYNTSFHAPT VSSTTSSSST TSLAANKGVN
SNSITSLNLE STSSVTSTAY TTDSVTSTTA LTSQGPSSSV VSSSLSSTTS LSTSIPVTSS
VAPAVTSTGS ETSSVVGSGT DSATSSSWTA ETSSSAITSS VAASVTPTSS SSASSWSSSS
EVDPSTAASA TGSSTSSIAT ASVSGSSTSS VATASATDSS TSSIAAASVT GSSTSSVATA
SVTDSSTSSV ATASATDSST SSIAVASVTG SSTSSVATAS ATDSSTSSVA TASITGSLSS
SIATASVTGS PTSSVTAVSS TSSVEGTASS TIAAAASAAT LSSDAASGSS TVTSSATASS
SSSAATTADS SVTTDTPSND FNANVDTAGL WYVSALSSYS VPAGFAWTTI DGFSVVMPSA
NAYKKRSLPI KATANPALNG AGTWKTIHTS ATTTAA
