YKT8_SCHPO
ID YKT8_SCHPO Reviewed; 554 AA.
AC Q9C101;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Uncharacterized MFS-type transporter PB1E7.08c;
GN ORFNames=SPAPB1E7.08c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1] {ECO:0000312|EMBL:CAC36925.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2] {ECO:0000305}
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3] {ECO:0000305}
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-13 AND SER-334, AND
RP IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum
CC {ECO:0000269|PubMed:16823372}. Membrane {ECO:0000255}; Multi-pass
CC membrane protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000255}.
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DR EMBL; CU329670; CAC36925.1; -; Genomic_DNA.
DR RefSeq; NP_594134.1; NM_001019558.2.
DR AlphaFoldDB; Q9C101; -.
DR SMR; Q9C101; -.
DR BioGRID; 280074; 5.
DR STRING; 4896.SPAPB1E7.08c.1; -.
DR TCDB; 2.A.1.19.38; the major facilitator superfamily (mfs).
DR iPTMnet; Q9C101; -.
DR MaxQB; Q9C101; -.
DR PaxDb; Q9C101; -.
DR PRIDE; Q9C101; -.
DR EnsemblFungi; SPAPB1E7.08c.1; SPAPB1E7.08c.1:pep; SPAPB1E7.08c.
DR GeneID; 2543660; -.
DR KEGG; spo:SPAPB1E7.08c; -.
DR PomBase; SPAPB1E7.08c; -.
DR VEuPathDB; FungiDB:SPAPB1E7.08c; -.
DR eggNOG; KOG0253; Eukaryota.
DR HOGENOM; CLU_001265_52_2_1; -.
DR InParanoid; Q9C101; -.
DR OMA; EIFPTKD; -.
DR PhylomeDB; Q9C101; -.
DR PRO; PR:Q9C101; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; ISM:PomBase.
DR GO; GO:0034220; P:ion transmembrane transport; IEA:UniProt.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 1: Evidence at protein level;
KW Endoplasmic reticulum; Membrane; Phosphoprotein; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..554
FT /note="Uncharacterized MFS-type transporter PB1E7.08c"
FT /id="PRO_0000372717"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 120..140
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 149..169
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 210..230
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 253..273
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 364..384
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 412..432
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 437..457
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 462..482
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 497..517
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 525..545
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 13
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 334
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 554 AA; 61233 MW; E82FE37B438ED1F5 CRC64;
MSSSIPPRLY DMSPTESKKQ EDVSETELVY PVELADATIQ PSKSDDDLFD SNDFSKTYLA
KSRILSNAMN EIGFGRYQWY LFFVAGFGWM SDNIWPVCTS LILMRLDEVD GPHPPAEGRA
PYLTLSQNLG LLVGAMVWSL SADTIGRRWA FNLTFLFTGV FAVIAGASPN FASICVFDAL
WSFGVGGNLP VDSAIFLEAL PSSHQWLLTV MSFWWAIGQV IANLVSWGLI SNFSCPDDES
VCHRADNKGW RYFLFTMGGM TLLMFAARFL VSVYESPKFY LAKGDDYKAV ETIHKIARIN
GKTCTLTVEE LYAIDRQEQE ESDLDDSKSS DAKSVTQGTT NLIVEKLRKY NFEHIRQCFG
SRKLAISSIL VILSWAVIGL AFPLYNAFLP YYLETRGNAN EPLSVAKTYR NSLIVSAIGV
PGSLIAGVLV EFRIGRKGTL CLSLILTGVF LFASTTAKTS NAYLGWNCTF SFFSDIMYGV
LYAYTPEVFP SKVRGTAVGL AASANRILGI FSPVIAMRAN LTTSAPIFVS GALFIFAGIL
VVFFPYEPRG KSSF
