ID   YKTD_BACSU              Reviewed;         304 AA.
AC   Q45500; Q796J5;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase YktD;
DE            EC=2.1.1.-;
GN   Name=yktD; OrderedLocusNames=BSU14690;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=I168;
RX   PubMed=1697575; DOI=10.1128/jb.172.9.5052-5063.1990;
RA   Hemilae H.O., Palva A., Paulin L., Arvidson S., Palva I.;
RT   "Secretory S complex of Bacillus subtilis: sequence analysis and identity
RT   to pyruvate dehydrogenase.";
RL   J. Bacteriol. 172:5052-5063(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=I168;
RX   PubMed=8990290; DOI=10.1128/jb.179.2.389-398.1997;
RA   Henriques A.O., Bryan E.M., Beall B.W., Moran C.P. Jr.;
RT   "cse15, cse60, and csk22 are new members of mother-cell-specific
RT   sporulation regulons in Bacillus subtilis.";
RL   J. Bacteriol. 179:389-398(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=I168;
RX   PubMed=8969500; DOI=10.1099/13500872-142-11-3033;
RA   Winters P., Caldwell R.M., Enfield L., Ferrari E.;
RT   "The ampS-nprE (124 degrees-127 degrees) region of the Bacillus subtilis
RT   168 chromosome: sequencing of a 27 kb segment and identification of several
RT   genes in the area.";
RL   Microbiology 142:3033-3037(1996).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [5]
RP   POSSIBLE FUNCTION.
RX   PubMed=17928718; DOI=10.1271/bbb.70223;
RA   Kimura K., Itoh Y.;
RT   "Determination and characterization of IS4Bsu1-insertion loci and
RT   identification of a new insertion sequence element of the IS256 family in a
RT   natto starter.";
RL   Biosci. Biotechnol. Biochem. 71:2458-2464(2007).
CC   -!- FUNCTION: May be involved in polyketide synthesis.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; AF012285; AAC24941.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB13342.1; -; Genomic_DNA.
DR   PIR; F69864; F69864.
DR   RefSeq; NP_389352.1; NC_000964.3.
DR   RefSeq; WP_003245561.1; NZ_JNCM01000035.1.
DR   AlphaFoldDB; Q45500; -.
DR   SMR; Q45500; -.
DR   STRING; 224308.BSU14690; -.
DR   PaxDb; Q45500; -.
DR   PRIDE; Q45500; -.
DR   EnsemblBacteria; CAB13342; CAB13342; BSU_14690.
DR   GeneID; 935978; -.
DR   KEGG; bsu:BSU14690; -.
DR   PATRIC; fig|224308.179.peg.1602; -.
DR   eggNOG; COG3315; Bacteria.
DR   InParanoid; Q45500; -.
DR   OMA; AFETIHY; -.
DR   PhylomeDB; Q45500; -.
DR   BioCyc; BSUB:BSU14690-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..304
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase YktD"
FT                   /id="PRO_0000360547"
FT   BINDING         134
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         163..164
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   304 AA;  34761 MW;  98043EEB1BD8BB32 CRC64;
     MRKNESSLTS LISAFARAYH SRYDTPLIFD DFIAKDLINE KEFIDISKNM IQEISFFNKE
     IAERLQNDPE KILKWVAQIQ LSPTPLARAS YCEKVLHNEL ILGAKQYVIL GAGLDTFCFR
     HPELENSLQV FEVDHPATQQ LKKNKLKDAN LTIPGHLHFV PMDFTKTFSY DPLLDEGFKN
     TKTFFSLLGV SYYVTREENA SLISNLFSHV PPGSSIVFDY ADETLFTAKG TSNRVEHMVK
     MAAASGEPMK SCFTYQEIEH LLESSGLLIY EHLSPDDIND LFFSNRKDNL SAFETIHYIH
     AVKK