YKY4_SCHPO
ID YKY4_SCHPO Reviewed; 707 AA.
AC Q9P7G0; Q9UTY0;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 95.
DE RecName: Full=Uncharacterized NOC2 family protein C1142.04;
GN ORFNames=SPAC1142.04;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1] {ECO:0000312|EMBL:CAB77011.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2] {ECO:0000305, ECO:0000312|EMBL:BAA87241.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-133, AND SUBCELLULAR
RP LOCATION.
RC STRAIN=ATCC 38364 / 968 {ECO:0000312|EMBL:BAA87241.1};
RX PubMed=10759889; DOI=10.1046/j.1365-2443.2000.00317.x;
RA Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T.,
RA Hiraoka Y.;
RT "Large-scale screening of intracellular protein localization in living
RT fission yeast cells by the use of a GFP-fusion genomic DNA library.";
RL Genes Cells 5:169-190(2000).
RN [3] {ECO:0000305}
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-112, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:10759889,
CC ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the NOC2 family. {ECO:0000255}.
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DR EMBL; CU329670; CAB77011.1; -; Genomic_DNA.
DR EMBL; AB027937; BAA87241.1; -; Genomic_DNA.
DR RefSeq; NP_594268.1; NM_001019691.2.
DR AlphaFoldDB; Q9P7G0; -.
DR BioGRID; 279119; 25.
DR STRING; 4896.SPAC1142.04.1; -.
DR iPTMnet; Q9P7G0; -.
DR MaxQB; Q9P7G0; -.
DR PaxDb; Q9P7G0; -.
DR PRIDE; Q9P7G0; -.
DR EnsemblFungi; SPAC1142.04.1; SPAC1142.04.1:pep; SPAC1142.04.
DR GeneID; 2542666; -.
DR KEGG; spo:SPAC1142.04; -.
DR PomBase; SPAC1142.04; -.
DR VEuPathDB; FungiDB:SPAC1142.04; -.
DR eggNOG; KOG2256; Eukaryota.
DR HOGENOM; CLU_011272_0_0_1; -.
DR InParanoid; Q9P7G0; -.
DR OMA; FPLRFHC; -.
DR PhylomeDB; Q9P7G0; -.
DR PRO; PR:Q9P7G0; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0030690; C:Noc1p-Noc2p complex; ISO:PomBase.
DR GO; GO:0030691; C:Noc2p-Noc3p complex; ISO:PomBase.
DR GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR InterPro; IPR005343; Noc2.
DR PANTHER; PTHR12687; PTHR12687; 1.
DR Pfam; PF03715; Noc2; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Nucleus; Phosphoprotein; Reference proteome.
FT CHAIN 1..707
FT /note="Uncharacterized NOC2 family protein C1142.04"
FT /id="PRO_0000326122"
FT REGION 15..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 667..707
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 659..700
FT /evidence="ECO:0000255"
FT COMPBIAS 15..55
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 667..692
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..707
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 112
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 707 AA; 81128 MW; FEF46CE1DD480176 CRC64;
MVKLSSIIKA RKANALAKKN DKIKKKDTDK GIRQKHSKKE GKDETLKRDV EKFIQNVNSE
DTPSEDDSMS MDAFLEGGFE ELDSANSNDA GSSRKRKNLP NENTQDSTSE SSEEEEDGLE
SYQKQLEGLK EKDPEFYKFL EQNDQDLLEF NAAETDAMAK EIDENERLKS SSGKIVLTSD
TIQQWQKLLE TNHSLTTLQK VVQAFKAAAF LNEEEAEDLK YTISDSKVFN DLLLLAIQYV
PKVLNYHVPI QEDAKGKKFI NTDSKVLPKL RPVLKSYGFS ILRLLEGMTD AKNISLLLRE
AQNVLPYMIT YRKFLKQFTQ ATVEVWSSTR DDSVRFSAVV LLRTLCLTAD ITLLEFVLKE
VYLGMARQSA YTTVHTLDKI NFLKNSAVNL FLLDAESCYL IGFRYIRQLA ITLRNTIHQP
SKDSRKPVQS WSYVHSLDFW ARLLSQAAWL SREKGVASEL QSLVYPLVQI ALGVIMSSPS
SQLFPMRFHI IRSLIYLSRH TGVFIPLAPS LFEVLDSSYV SRKAKASTLK PLDFDVELRA
SSSYLRTKVY QDGLIDQLLE LLSEYYVLYA TDISFPELVI PAIVRSKRFA KRSKNAKLNR
GLLTLVNRLE QQSKFMTEKR NQQKFAPIDS DSVEQFAQTI DWQQTPLGIY VVTQRQTREE
QRKLIRESVQ QDQEHKEQMR QKKKQALKSD DIELDDLSEE EAEDIDE