YKY5_YEAST
ID YKY5_YEAST Reviewed; 525 AA.
AC Q02203; D6VXU1;
DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 2.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Uncharacterized protein YKR005C;
DE Flags: Precursor;
GN OrderedLocusNames=YKR005C; ORFNames=YK104;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=1441752; DOI=10.1002/yea.320080908;
RA Duesterhoeft A., Philippsen P.;
RT "DNA sequencing and analysis of a 24.7 kb segment encompassing centromere
RT CEN11 of Saccharomyces cerevisiae reveals nine previously unknown open
RT reading frames.";
RL Yeast 8:749-759(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8196765; DOI=10.1038/369371a0;
RA Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V.,
RA Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P.,
RA Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L.,
RA Daignan-Fornier B., del Rey F., Dion C., Domdey H., Duesterhoeft A.,
RA Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H.,
RA Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L.,
RA Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M.,
RA Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H.,
RA Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J.,
RA Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H.,
RA Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J.,
RA Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S.,
RA Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F.,
RA Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R.,
RA Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W.,
RA Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M.,
RA Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C.,
RA Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H.,
RA Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L.,
RA van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S.,
RA von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M.,
RA Becker I., Mewes H.-W.;
RT "Complete DNA sequence of yeast chromosome XI.";
RL Nature 369:371-378(1994).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 79-525.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [5]
RP IDENTIFICATION OF INTRON.
RX PubMed=17101987; DOI=10.1073/pnas.0605645103;
RA Miura F., Kawaguchi N., Sese J., Toyoda A., Hattori M., Morishita S.,
RA Ito T.;
RT "A large-scale full-length cDNA analysis to explore the budding yeast
RT transcriptome.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:17846-17851(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA46247.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAA82075.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; X65124; CAA46247.1; ALT_SEQ; Genomic_DNA.
DR EMBL; Z28230; CAA82075.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AY558315; AAS56641.1; -; Genomic_DNA.
DR EMBL; BK006944; DAA09161.1; -; Genomic_DNA.
DR PIR; S25817; S25817.
DR RefSeq; NP_012930.2; NM_001179795.1.
DR AlphaFoldDB; Q02203; -.
DR BioGRID; 34137; 93.
DR DIP; DIP-4606N; -.
DR STRING; 4932.YKR005C; -.
DR PaxDb; Q02203; -.
DR PRIDE; Q02203; -.
DR EnsemblFungi; YKR005C_mRNA; YKR005C; YKR005C.
DR GeneID; 853874; -.
DR KEGG; sce:YKR005C; -.
DR SGD; S000001713; YKR005C.
DR VEuPathDB; FungiDB:YKR005C; -.
DR eggNOG; ENOG502S2FV; Eukaryota.
DR HOGENOM; CLU_518965_0_0_1; -.
DR InParanoid; Q02203; -.
DR OMA; SITTLMM; -.
DR BioCyc; YEAST:G3O-31983-MON; -.
DR PRO; PR:Q02203; -.
DR Proteomes; UP000002311; Chromosome XI.
DR RNAct; Q02203; protein.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005739; C:mitochondrion; HDA:SGD.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..525
FT /note="Uncharacterized protein YKR005C"
FT /id="PRO_0000203192"
FT TOPO_DOM 22..448
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 449..469
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 470..525
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 242..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 525 AA; 58710 MW; 59252E1F0FCD6EF8 CRC64;
MLECLSALLV LFAGGGGSVL AAVQSKTVAD PNLCPGYNSQ LISPFLSSCK RNLSECVSRY
FDEQYAFCRS CVTVNNETME DLDNCKCLQC ALSSLNNSCF HDYCTSKDEY DKLQIVVEQF
QLTNGVLDDG EILKPRGNKF SSRKLSYFVG QNNTLFRNPL QFEKNQLISA LLTSLTNNQK
TISSVDMFEV VDANNEVQYL RERTISGKTL SPATGYEEEN DGDCSVKDKK WEGKIEYHEN
KKVSSENCSK DTDDKSGSKK ERNTKAPLFH TATEIHMTRW SSWRPKKIFT RYLVNEYQSP
KIITTVNRFY RTKTDTETGT TLITSTKAKR RWFPRTKIVT STATSTFLSI TTTTTTNAIA
TKSLVAVLNP DGLNKKAGIN FGLFSANGEL ASPDEGGTPT VVRRDKISDP GAANEQATLF
STTFSQVPHL PELDSGEFIS AASQLDKRIF IFTAITVSIT TLMMLGFSYR SRVSFRDHSI
DDSDDDNDWS DDEVEFDEEY FYSLPVSIPE KGISLDKMAQ QLGVE
