CBIN_STRCO
ID CBIN_STRCO Reviewed; 118 AA.
AC O54189;
DT 27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 25-MAY-2022, entry version 116.
DE RecName: Full=Cobalt transport protein CbiN {ECO:0000255|HAMAP-Rule:MF_00330};
DE AltName: Full=Energy-coupling factor transporter probable substrate-capture protein CbiN {ECO:0000255|HAMAP-Rule:MF_00330};
DE Short=ECF transporter S component CbiN {ECO:0000255|HAMAP-Rule:MF_00330};
GN Name=cbiN {ECO:0000255|HAMAP-Rule:MF_00330}; OrderedLocusNames=SCO5960;
GN ORFNames=SC7H1.30c;
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145;
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- FUNCTION: Part of the energy-coupling factor (ECF) transporter complex
CC CbiMNOQ involved in cobalt import. {ECO:0000255|HAMAP-Rule:MF_00330}.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00330}.
CC -!- SUBUNIT: Forms an energy-coupling factor (ECF) transporter complex
CC composed of an ATP-binding protein (A component, CbiO), a transmembrane
CC protein (T component, CbiQ) and 2 possible substrate-capture proteins
CC (S components, CbiM and CbiN) of unknown stoichimetry.
CC {ECO:0000255|HAMAP-Rule:MF_00330}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00330};
CC Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00330}.
CC -!- SIMILARITY: Belongs to the CbiN family. {ECO:0000255|HAMAP-
CC Rule:MF_00330}.
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DR EMBL; AL939125; CAA16217.1; -; Genomic_DNA.
DR PIR; T35725; T35725.
DR RefSeq; NP_630077.1; NC_003888.3.
DR RefSeq; WP_011030566.1; NZ_VNID01000007.1.
DR AlphaFoldDB; O54189; -.
DR STRING; 100226.SCO5960; -.
DR GeneID; 1101402; -.
DR KEGG; sco:SCO5960; -.
DR PATRIC; fig|100226.15.peg.6057; -.
DR eggNOG; COG1930; Bacteria.
DR HOGENOM; CLU_136197_2_0_11; -.
DR InParanoid; O54189; -.
DR OMA; TEIEPDY; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR HAMAP; MF_00330; CbiN; 1.
DR InterPro; IPR003705; CbiN.
DR PANTHER; PTHR38662; PTHR38662; 1.
DR Pfam; PF02553; CbiN; 1.
DR TIGRFAMs; TIGR01165; cbiN; 1.
PE 3: Inferred from homology;
KW Cell membrane; Cobalamin biosynthesis; Cobalt; Cobalt transport;
KW Ion transport; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..118
FT /note="Cobalt transport protein CbiN"
FT /id="PRO_0000134699"
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00330"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00330"
FT REGION 99..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 118 AA; 12271 MW; 54927C086E905C13 CRC64;
MSRNTRINAL LLLAVAALAV LPLVLGLGDH KEEPFAGADA EAETAITEIE PDYEPWFSPL
HEPPSGEVES ALFALQAALG AGVLAYYFGL RRGRRQGEER ASAASGAAAA PGDAPEGD