ID   CBIO_SALPA              Reviewed;         271 AA.
AC   Q5PDU4;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Cobalt import ATP-binding protein CbiO {ECO:0000255|HAMAP-Rule:MF_01710};
DE            EC=7.-.-.- {ECO:0000255|HAMAP-Rule:MF_01710};
DE   AltName: Full=Energy-coupling factor transporter ATP-binding protein CbiO {ECO:0000255|HAMAP-Rule:MF_01710};
DE            Short=ECF transporter A component CbiO {ECO:0000255|HAMAP-Rule:MF_01710};
GN   Name=cbiO {ECO:0000255|HAMAP-Rule:MF_01710}; OrderedLocusNames=SPA0851;
OS   Salmonella paratyphi A (strain ATCC 9150 / SARB42).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=295319;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 9150 / SARB42;
RX   PubMed=15531882; DOI=10.1038/ng1470;
RA   McClelland M., Sanderson K.E., Clifton S.W., Latreille P., Porwollik S.,
RA   Sabo A., Meyer R., Bieri T., Ozersky P., McLellan M., Harkins C.R.,
RA   Wang C., Nguyen C., Berghoff A., Elliott G., Kohlberg S., Strong C., Du F.,
RA   Carter J., Kremizki C., Layman D., Leonard S., Sun H., Fulton L., Nash W.,
RA   Miner T., Minx P., Delehaunty K., Fronick C., Magrini V., Nhan M.,
RA   Warren W., Florea L., Spieth J., Wilson R.K.;
RT   "Comparison of genome degradation in Paratyphi A and Typhi, human-
RT   restricted serovars of Salmonella enterica that cause typhoid.";
RL   Nat. Genet. 36:1268-1274(2004).
CC   -!- FUNCTION: Part of the energy-coupling factor (ECF) transporter complex
CC       CbiMNOQ involved in cobalt import. Presumably responsible for energy
CC       coupling to the transport system. {ECO:0000255|HAMAP-Rule:MF_01710}.
CC   -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01710}.
CC   -!- SUBUNIT: Forms an energy-coupling factor (ECF) transporter complex
CC       composed of an ATP-binding protein (A component, CbiO), a transmembrane
CC       protein (T component, CbiQ) and 2 possible substrate-capture proteins
CC       (S components, CbiM and CbiN) of unknown stoichimetry.
CC       {ECO:0000255|HAMAP-Rule:MF_01710}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01710}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01710}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Cobalt importer
CC       (TC 3.A.1.18.1) family. {ECO:0000255|HAMAP-Rule:MF_01710}.
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DR   EMBL; CP000026; AAV76839.1; -; Genomic_DNA.
DR   RefSeq; WP_000881534.1; NC_006511.1.
DR   AlphaFoldDB; Q5PDU4; -.
DR   SMR; Q5PDU4; -.
DR   EnsemblBacteria; AAV76839; AAV76839; SPA0851.
DR   KEGG; spt:SPA0851; -.
DR   HOGENOM; CLU_000604_1_22_6; -.
DR   OMA; DIVPLYC; -.
DR   UniPathway; UPA00148; -.
DR   Proteomes; UP000008185; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006824; P:cobalt ion transport; IEA:UniProtKB-KW.
DR   CDD; cd03225; ABC_cobalt_CbiO_domain1; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR015856; ABC_transpr_CbiO/EcfA_su.
DR   InterPro; IPR005876; Co_trans_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01166; cbiO; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51246; CBIO; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell inner membrane; Cell membrane; Cobalamin biosynthesis;
KW   Cobalt; Cobalt transport; Ion transport; Membrane; Nucleotide-binding;
KW   Translocase; Transport.
FT   CHAIN           1..271
FT                   /note="Cobalt import ATP-binding protein CbiO"
FT                   /id="PRO_0000287980"
FT   DOMAIN          2..236
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01710"
FT   BINDING         34..41
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01710"
SQ   SEQUENCE   271 AA;  30132 MW;  1CD7A8848A767D97 CRC64;
     MLATSDLWFR YQDEPVLKGL NLDFSLSPVT GLVGANGCGK STLFMNLSGL LRPQKGAVLW
     QGKPLDYSKR GLLALRQQVA TVFQDPEQQI FYTDIDSDIA FSLRNLGVPE AEITRRVDEA
     LTLVDAQHFR HQPIQCLSHG QKKRVAIAGA LVLQARYLLL DEPTAGLDPA GRTQMIAIIR
     RIVAQGNHVI ISSHDIDLIY EISDAVYVLR QGQILMHGAP GEVFACTEAM EHAGLTQPWL
     VKLHTQLGLP LCKTETEFFH RMQKCAFKEA S