ID   YL049_YEAST             Reviewed;         428 AA.
AC   Q12110; D6VY51;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 133.
DE   RecName: Full=Uncharacterized protein YLR049C;
GN   OrderedLocusNames=YLR049C; ORFNames=L2121;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169871;
RA   Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W.,
RA   Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A.,
RA   Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K.,
RA   Heuss-Neitzel D., Hilbert H., Hilger F., Kleine K., Koetter P., Louis E.J.,
RA   Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S.,
RA   Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D.,
RA   Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M.,
RA   Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P.,
RA   Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M.,
RA   Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K.,
RA   Zollner A., Hani J., Hoheisel J.D.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.";
RL   Nature 387:87-90(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX   PubMed=14562106; DOI=10.1038/nature02046;
RA   Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA   O'Shea E.K., Weissman J.S.;
RT   "Global analysis of protein expression in yeast.";
RL   Nature 425:737-741(2003).
RN   [4]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-127, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=YAL6B;
RX   PubMed=15665377; DOI=10.1074/mcp.m400219-mcp200;
RA   Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J., Mann M.,
RA   Jensen O.N.;
RT   "Quantitative phosphoproteomics applied to the yeast pheromone signaling
RT   pathway.";
RL   Mol. Cell. Proteomics 4:310-327(2005).
RN   [5]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-127, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=19779198; DOI=10.1126/science.1172867;
RA   Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
RT   "Global analysis of Cdk1 substrate phosphorylation sites provides insights
RT   into evolution.";
RL   Science 325:1682-1686(2009).
CC   -!- MISCELLANEOUS: Present with 339 molecules/cell in log phase SD medium.
CC       {ECO:0000269|PubMed:14562106}.
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DR   EMBL; Z73221; CAA97579.1; -; Genomic_DNA.
DR   EMBL; X94607; CAA64296.1; -; Genomic_DNA.
DR   EMBL; BK006945; DAA09367.1; -; Genomic_DNA.
DR   PIR; S61623; S61623.
DR   RefSeq; NP_013150.1; NM_001181936.1.
DR   AlphaFoldDB; Q12110; -.
DR   SMR; Q12110; -.
DR   BioGRID; 31324; 27.
DR   DIP; DIP-1211N; -.
DR   IntAct; Q12110; 1.
DR   MINT; Q12110; -.
DR   STRING; 4932.YLR049C; -.
DR   iPTMnet; Q12110; -.
DR   PaxDb; Q12110; -.
DR   PRIDE; Q12110; -.
DR   EnsemblFungi; YLR049C_mRNA; YLR049C; YLR049C.
DR   GeneID; 850738; -.
DR   KEGG; sce:YLR049C; -.
DR   SGD; S000004039; YLR049C.
DR   VEuPathDB; FungiDB:YLR049C; -.
DR   eggNOG; ENOG502RZ58; Eukaryota.
DR   HOGENOM; CLU_052997_0_0_1; -.
DR   InParanoid; Q12110; -.
DR   OMA; SYYHELD; -.
DR   BioCyc; YEAST:G3O-32205-MON; -.
DR   PRO; PR:Q12110; -.
DR   Proteomes; UP000002311; Chromosome XII.
DR   RNAct; Q12110; protein.
PE   1: Evidence at protein level;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..428
FT                   /note="Uncharacterized protein YLR049C"
FT                   /id="PRO_0000247204"
FT   REGION          72..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         127
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:15665377,
FT                   ECO:0007744|PubMed:19779198"
SQ   SEQUENCE   428 AA;  49493 MW;  9414BB6CF379E682 CRC64;
     MVNNIMHEYV PPSQRLFHSR HRITRNDLKE EALHSGTTDW TTILDTTIDK DTNLISYAVP
     IIDNFAIPRA NSQGSPVAPS PNHRSTMYSS SSSSASSVFS DGLFTPNNNR NSSGSSSLVI
     RPQKNLSVDS LIQENKRKIN SEKESLSLIA NNNDETLCTH TDPSIQNLIK SETKRNILNL
     KFQNRNLFRR ELKLEKFWSN LRSCHTSGDE TDLLLVISKH NLYWFGIPND FRLPIYKRCL
     YHYSELDEAG FFSQYANNSL YLAIRKCCNN EEQETLSRSI FINLTKNVTW LNSRFDDNKD
     NKNSYTVTEG KFYQDFPNLY YHLKDKLKLN VIMDFIKPVI RNFMTNALNK HKLDGIGLEL
     LDILIVTTYY GPNKINAFLM DTFILNLLKQ CHYKFFVSNI SELVIQISKI DCDLVILLED
     LRSRIDLD