ID   YL056_YEAST             Reviewed;         298 AA.
AC   Q12177; D6VXV2;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 138.
DE   RecName: Full=Uncharacterized protein YLL056C;
GN   OrderedLocusNames=YLL056C; ORFNames=L0575;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169871;
RA   Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W.,
RA   Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A.,
RA   Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K.,
RA   Heuss-Neitzel D., Hilbert H., Hilger F., Kleine K., Koetter P., Louis E.J.,
RA   Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S.,
RA   Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D.,
RA   Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M.,
RA   Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P.,
RA   Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M.,
RA   Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K.,
RA   Zollner A., Hani J., Hoheisel J.D.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.";
RL   Nature 387:87-90(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
RN   [4]
RP   INDUCTION.
RX   PubMed=11223942;
RX   DOI=10.1002/1097-0061(20010315)18:4<325::aid-yea669>3.0.co;2-k;
RA   Zhang N., Merlotti C., Wu J., Ismail T., El-Moghazy A.-N., Khan S.A.,
RA   Butt A., Gardner D.C.J., Sims P.F.G., Oliver S.G.;
RT   "Functional analysis of six novel ORFs on the left arm of chromosome XII of
RT   Saccharomyces cerevisiae reveals three of them responding to S-
RT   starvation.";
RL   Yeast 18:325-334(2001).
CC   -!- INDUCTION: Highly induced under sulfur starvation conditions.
CC       {ECO:0000269|PubMed:11223942}.
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. {ECO:0000305}.
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DR   EMBL; Z47973; CAA88001.1; -; Genomic_DNA.
DR   EMBL; Z73161; CAA97509.1; -; Genomic_DNA.
DR   EMBL; AY558193; AAS56519.1; -; Genomic_DNA.
DR   EMBL; BK006945; DAA09268.1; -; Genomic_DNA.
DR   PIR; S50964; S50964.
DR   RefSeq; NP_013044.1; NM_001181876.1.
DR   AlphaFoldDB; Q12177; -.
DR   SMR; Q12177; -.
DR   BioGRID; 31259; 50.
DR   DIP; DIP-8912N; -.
DR   IntAct; Q12177; 1.
DR   STRING; 4932.YLL056C; -.
DR   PaxDb; Q12177; -.
DR   PRIDE; Q12177; -.
DR   EnsemblFungi; YLL056C_mRNA; YLL056C; YLL056C.
DR   GeneID; 850670; -.
DR   KEGG; sce:YLL056C; -.
DR   SGD; S000003979; YLL056C.
DR   VEuPathDB; FungiDB:YLL056C; -.
DR   eggNOG; KOG1502; Eukaryota.
DR   HOGENOM; CLU_007383_12_3_1; -.
DR   InParanoid; Q12177; -.
DR   OMA; RFAENCE; -.
DR   BioCyc; MetaCyc:G3O-32155-MON; -.
DR   BioCyc; YEAST:G3O-32155-MON; -.
DR   PRO; PR:Q12177; -.
DR   Proteomes; UP000002311; Chromosome XII.
DR   RNAct; Q12177; protein.
DR   GO; GO:0005737; C:cytoplasm; IDA:SGD.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IDA:SGD.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..298
FT                   /note="Uncharacterized protein YLL056C"
FT                   /id="PRO_0000247152"
SQ   SEQUENCE   298 AA;  32148 MW;  51E1924BC3EB859B CRC64;
     MKVFITGASG FIGSAVLSEL ISSGHEVVGL ARSDEAAAKI KSIDPAAKIL RGDLKDLEIL
     KKGATESDGV IHLGFVHDFK NFEQCCEIDR QATVAMLESL KGSNKPFLYT NGTLSLRPNK
     VANEQDGIDE DSKILRAVTE QVALSYKDKG VSARIVRLPF SVHGKGDKAF VPILMNIAKA
     AGKSGYVGQG TNAWAAVHRL DTAPLFRLVL EKGKTGQVYH CVGEQGIPFK DIARVIGEIL
     NVPVASIPVD DAESHFGFLT CFVTRDGPVS SEGTRKELGW QPQQIGLLED IRANYSLN