YL108_YEAST
ID YL108_YEAST Reviewed; 485 AA.
AC Q12259; D6VYA8;
DT 25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 143.
DE RecName: Full=BTB/POZ domain-containing protein YLR108C;
GN OrderedLocusNames=YLR108C; ORFNames=L2913;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 90840 / EAY235 / FY23;
RX PubMed=9090053;
RX DOI=10.1002/(sici)1097-0061(19970315)13:3<241::aid-yea61>3.0.co;2-#;
RA Verhasselt P., Volckaert G.;
RT "Sequence analysis of a 37.6 kbp cosmid clone from the right arm of
RT Saccharomyces cerevisiae chromosome XII, carrying YAP3, HOG1, SNR6, tRNA-
RT Arg3 and 23 new open reading frames, among which several homologies to
RT proteins involved in cell division control and to mammalian growth factors
RT and other animal proteins are found.";
RL Yeast 13:241-250(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169871;
RA Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W.,
RA Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A.,
RA Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K.,
RA Heuss-Neitzel D., Hilbert H., Hilger F., Kleine K., Koetter P., Louis E.J.,
RA Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S.,
RA Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D.,
RA Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M.,
RA Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P.,
RA Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M.,
RA Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K.,
RA Zollner A., Hani J., Hoheisel J.D.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.";
RL Nature 387:87-90(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [5]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:14562095}.
CC -!- MISCELLANEOUS: Present with 189 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; X89514; CAA61686.1; -; Genomic_DNA.
DR EMBL; U53878; AAB67553.1; -; Genomic_DNA.
DR EMBL; Z73280; CAA97674.1; -; Genomic_DNA.
DR EMBL; BK006945; DAA09424.1; -; Genomic_DNA.
DR PIR; S64945; S64945.
DR RefSeq; NP_013209.1; NM_001181995.1.
DR AlphaFoldDB; Q12259; -.
DR BioGRID; 31381; 45.
DR DIP; DIP-4075N; -.
DR IntAct; Q12259; 7.
DR MINT; Q12259; -.
DR STRING; 4932.YLR108C; -.
DR iPTMnet; Q12259; -.
DR MaxQB; Q12259; -.
DR PaxDb; Q12259; -.
DR PRIDE; Q12259; -.
DR EnsemblFungi; YLR108C_mRNA; YLR108C; YLR108C.
DR GeneID; 850798; -.
DR KEGG; sce:YLR108C; -.
DR SGD; S000004098; YLR108C.
DR VEuPathDB; FungiDB:YLR108C; -.
DR eggNOG; ENOG502QRM9; Eukaryota.
DR GeneTree; ENSGT00940000176731; -.
DR HOGENOM; CLU_017395_2_1_1; -.
DR InParanoid; Q12259; -.
DR OMA; CISICDL; -.
DR BioCyc; YEAST:G3O-32256-MON; -.
DR PRO; PR:Q12259; -.
DR Proteomes; UP000002311; Chromosome XII.
DR RNAct; Q12259; protein.
DR GO; GO:0005634; C:nucleus; HDA:SGD.
DR Gene3D; 3.30.710.10; -; 2.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; SSF54695; 2.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome.
FT CHAIN 1..485
FT /note="BTB/POZ domain-containing protein YLR108C"
FT /id="PRO_0000247339"
FT DOMAIN 26..121
FT /note="BTB"
SQ SEQUENCE 485 AA; 55601 MW; 42A24A0F9C965133 CRC64;
MSGQKGEIVV YTKELETTPE LLPNHEVFKI RIGQKLFEIS GATLNSDAPN FFTQFFNTHD
KNTILFVDRS EDVFIIIYRH LQGYFPDIKN EVQFTCLFAD ALYFQLPKLV KLIKEYDYHF
TNIGGVPFKV PKSLFHEEGN RLNYFETISR ISYEEIEKWE SNKKPGFPPL LPPSYIARSP
EFFRDILSLL GGSKLELSEE RTASLIKECR YYRLNRLEQE LVRAKIIYNP LTNCQEVCIA
LDSVSKKGVT IERLTSLHTG NQSLAVSSCL NGTEGEKAAT GFHKTETDSG NNDEYEPPTK
KVKHCIERHW SMLKYQRPYI DTVSHDLIFQ LHSNQCKIIF NKKNKTVHVD LSREAAVLFE
NKFSDVLLEN PDFKIDLSEY KVKLRDSQMQ VESHLIIPAC VSICDLTVNG AKCCNIFSLV
NDSKCKGRVL DCTNLKVLNC VHGLKLHLSK SMWKLGTNNG RIILVAVKAE TFSGTKEYCK
MIDFL
