YL149_YEAST
ID YL149_YEAST Reviewed; 730 AA.
AC Q99296; D6VYE4;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 147.
DE RecName: Full=Uncharacterized protein YLR149C;
GN OrderedLocusNames=YLR149C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169871;
RA Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W.,
RA Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A.,
RA Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K.,
RA Heuss-Neitzel D., Hilbert H., Hilger F., Kleine K., Koetter P., Louis E.J.,
RA Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S.,
RA Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D.,
RA Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M.,
RA Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P.,
RA Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M.,
RA Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K.,
RA Zollner A., Hani J., Hoheisel J.D.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.";
RL Nature 387:87-90(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-82, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ADR376;
RX PubMed=17330950; DOI=10.1021/pr060559j;
RA Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,
RA Elias J.E., Gygi S.P.;
RT "Large-scale phosphorylation analysis of alpha-factor-arrested
RT Saccharomyces cerevisiae.";
RL J. Proteome Res. 6:1190-1197(2007).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-82; SER-89 AND SER-651, AND
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=18407956; DOI=10.1074/mcp.m700468-mcp200;
RA Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
RT "A multidimensional chromatography technology for in-depth phosphoproteome
RT analysis.";
RL Mol. Cell. Proteomics 7:1389-1396(2008).
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-483 AND SER-651, AND
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19779198; DOI=10.1126/science.1172867;
RA Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
RT "Global analysis of Cdk1 substrate phosphorylation sites provides insights
RT into evolution.";
RL Science 325:1682-1686(2009).
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DR EMBL; U53879; AAB82383.1; -; Genomic_DNA.
DR EMBL; Z73321; CAA97721.1; -; Genomic_DNA.
DR EMBL; BK006945; DAA09460.1; -; Genomic_DNA.
DR PIR; S64998; S64998.
DR RefSeq; NP_013250.1; NM_001182036.1.
DR AlphaFoldDB; Q99296; -.
DR BioGRID; 31418; 167.
DR IntAct; Q99296; 3.
DR MINT; Q99296; -.
DR STRING; 4932.YLR149C; -.
DR iPTMnet; Q99296; -.
DR MaxQB; Q99296; -.
DR PaxDb; Q99296; -.
DR PRIDE; Q99296; -.
DR TopDownProteomics; Q99296; -.
DR EnsemblFungi; YLR149C_mRNA; YLR149C; YLR149C.
DR GeneID; 850841; -.
DR KEGG; sce:YLR149C; -.
DR SGD; S000004139; YLR149C.
DR VEuPathDB; FungiDB:YLR149C; -.
DR eggNOG; KOG4532; Eukaryota.
DR HOGENOM; CLU_027079_0_0_1; -.
DR InParanoid; Q99296; -.
DR OMA; NSWARRS; -.
DR BioCyc; YEAST:G3O-32285-MON; -.
DR PRO; PR:Q99296; -.
DR Proteomes; UP000002311; Chromosome XII.
DR RNAct; Q99296; protein.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR019417; DUF2415.
DR InterPro; IPR011044; Quino_amine_DH_bsu.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR Pfam; PF10313; DUF2415; 1.
DR SUPFAM; SSF50969; SSF50969; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..730
FT /note="Uncharacterized protein YLR149C"
FT /id="PRO_0000262875"
FT REGION 82..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 447..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 82
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:17330950,
FT ECO:0007744|PubMed:18407956"
FT MOD_RES 89
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:18407956"
FT MOD_RES 483
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19779198"
FT MOD_RES 651
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:18407956,
FT ECO:0007744|PubMed:19779198"
SQ SEQUENCE 730 AA; 82799 MW; C0EC67BF0623A318 CRC64;
MTIDGTGQSK EALQDERLNT GSDKVYQNYM MPALELYDAK VSINHWQLRD CIKPGSMNQS
KLYYIYDHSI RVLDTDSSVL RSPVRRHNSI QPSNSGKNST EKTSTKGSRT TGSYISKNLH
VPSEKLVEFN FKPRCFTELN GLTVCGGLIG SDDKGFPSNW NRLAQDANIS LPPPSQPINI
SKNISFPINS HYSNPNIWKG IVEFYNQETD TMMTFTLGQF INNCVTLYDR ASMQFDLFAC
NNDGHLYQCD VSNRDVTLVK RYADLKFPLN NASLSHDGQT MVVSGDSNKF AVYNQNELTN
QFSLHYDNHP SWGSSVNRVR RIPRFALPDE SEYIENIYEA PNSDHGFYNS FSENDLQFAT
VFQNGTCAIY DIRNMATPMA EISSTRPHSH NGAFRVCRFS YGLDDLLFIS EHQGRVHVVD
TRNYVNHQVI VIPDKVNMEY INERKHNTNH NFTTNNNNEN ESNDSKNELQ GADYRSLSRR
RFSLPSMPNV TTEPWITMAQ RIPKKYLEPQ ILPFPKVMDK ISNESVLFST KGSSSSDVAH
PYKRRCSFRV RRVSTSAPTA DYSNNNVNAS LGTPAADSIA TSSSNSAPQN LIDPLILSHQ
QASNDVFEDD EYYEAYNDVH STYRVSSDYH GVSARAFESF LRPPSTPDLP SDDDNFAANS
RNNRGTSNFL RRPVITTQES NEFSEENNIS GIDWVEDRNG SSLIIGTDYG IMRWNINSWA
RRSFSSYDLC
