YL173_YEAST
ID YL173_YEAST Reviewed; 608 AA.
AC Q06247; D6VYH7;
DT 25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=Putative uncharacterized protein YLR173W;
GN OrderedLocusNames=YLR173W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169871;
RA Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W.,
RA Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A.,
RA Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K.,
RA Heuss-Neitzel D., Hilbert H., Hilger F., Kleine K., Koetter P., Louis E.J.,
RA Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S.,
RA Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D.,
RA Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M.,
RA Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P.,
RA Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M.,
RA Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K.,
RA Zollner A., Hani J., Hoheisel J.D.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.";
RL Nature 387:87-90(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-24 AND SER-27, AND
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19779198; DOI=10.1126/science.1172867;
RA Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
RT "Global analysis of Cdk1 substrate phosphorylation sites provides insights
RT into evolution.";
RL Science 325:1682-1686(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U17246; AAB67465.1; -; Genomic_DNA.
DR EMBL; AY692703; AAT92722.1; -; Genomic_DNA.
DR EMBL; BK006945; DAA09493.1; -; Genomic_DNA.
DR PIR; S51418; S51418.
DR RefSeq; NP_013274.1; NM_001182060.1.
DR AlphaFoldDB; Q06247; -.
DR BioGRID; 31444; 68.
DR DIP; DIP-4805N; -.
DR IntAct; Q06247; 2.
DR STRING; 4932.YLR173W; -.
DR iPTMnet; Q06247; -.
DR MaxQB; Q06247; -.
DR PaxDb; Q06247; -.
DR PRIDE; Q06247; -.
DR EnsemblFungi; YLR173W_mRNA; YLR173W; YLR173W.
DR GeneID; 850870; -.
DR KEGG; sce:YLR173W; -.
DR SGD; S000004163; YLR173W.
DR VEuPathDB; FungiDB:YLR173W; -.
DR eggNOG; ENOG502R0JC; Eukaryota.
DR HOGENOM; CLU_035072_0_0_1; -.
DR InParanoid; Q06247; -.
DR OMA; DWIRYIN; -.
DR BioCyc; YEAST:G3O-32300-MON; -.
DR PRO; PR:Q06247; -.
DR Proteomes; UP000002311; Chromosome XII.
DR RNAct; Q06247; protein.
DR GO; GO:0000329; C:fungal-type vacuole membrane; HDA:SGD.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR InterPro; IPR046368; Tag1.
DR PANTHER; PTHR35895; PTHR35895; 2.
PE 1: Evidence at protein level;
KW Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..608
FT /note="Putative uncharacterized protein YLR173W"
FT /id="PRO_0000247113"
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 24
FT /note="Phosphothreonine"
FT /evidence="ECO:0007744|PubMed:19779198"
FT MOD_RES 27
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19779198"
FT CARBOHYD 115
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 141
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 169
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 407
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 425
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 449
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 453
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 527
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 580
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 608 AA; 69606 MW; 8185932AD3ACD249 CRC64;
MHTNSPLRAD NQDLETQPLL RPNTEESQLL NDEVRINVAN ETLIKSRWRS IKCLIIYLLG
IVLLSFFGVS IVQYIRGHVP PTDVIEKNLV QVTNFKLVEF QLDGWKDNMG SDLNNDTGKY
LQVSIHSQIW FDYDKWPGTE NDSDARSQRD WIRYINEKVL KTICIDLNNV TTFDGDLVFK
NKLGDVVGME PICFNLAHRQ INNLQFKILV KPSIWKIVKV LKKFWNRDFE SLNIKSNLDM
TIFKRKFGTR FNLLKLNDEI LDWKDIIDWE KISATPLRMI QNMIDGISLQ GFTLRDSSSD
GFHADMRLNP ITILGGVDWL HLPPGTSIPF INWEIKLPDC NGEPAIAIPT LSCFNEPINL
HHDKDNIVVC LQNEIEGPLP DELLYQECPQ NSLTPMSQIV NAVLNQNETV TFAARGHVLE
DGIDNNSLIP ADMLEDIFQE ASFIPITTNA TFNSSELIQE FQINDLQLRW AARKKLSLVG
TFLGFFDLSF YETHQQDRVR IDTIRGQIDL YHNDINFLNL PMKQWINSSS HILHDEDTGN
TQMKLQFDLE NDDMEVVNSL ELTRTLNEIL FQGFTVIHFN ATIDASLTTA LGPWVLTGLA
GEGDTLVT
