ID   YL281_YEAST             Reviewed;         155 AA.
AC   Q05863; D6VYS6;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=Uncharacterized peptide chain release factor-like protein YLR281C, mitochondrial;
DE   Flags: Precursor;
GN   OrderedLocusNames=YLR281C;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169871;
RA   Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W.,
RA   Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A.,
RA   Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K.,
RA   Heuss-Neitzel D., Hilbert H., Hilger F., Kleine K., Koetter P., Louis E.J.,
RA   Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S.,
RA   Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D.,
RA   Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M.,
RA   Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P.,
RA   Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M.,
RA   Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K.,
RA   Zollner A., Hani J., Hoheisel J.D.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.";
RL   Nature 387:87-90(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
RN   [4]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=14562095; DOI=10.1038/nature02026;
RA   Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA   Weissman J.S., O'Shea E.K.;
RT   "Global analysis of protein localization in budding yeast.";
RL   Nature 425:686-691(2003).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:14562095}.
CC   -!- SIMILARITY: Belongs to the prokaryotic/mitochondrial release factor
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U17243; AAB67327.1; -; Genomic_DNA.
DR   EMBL; AY557931; AAS56257.1; -; Genomic_DNA.
DR   EMBL; BK006945; DAA09592.1; -; Genomic_DNA.
DR   PIR; S50367; S50367.
DR   RefSeq; NP_013383.1; NM_001182168.1.
DR   AlphaFoldDB; Q05863; -.
DR   SMR; Q05863; -.
DR   BioGRID; 31547; 253.
DR   DIP; DIP-2590N; -.
DR   STRING; 4932.YLR281C; -.
DR   MaxQB; Q05863; -.
DR   PaxDb; Q05863; -.
DR   PRIDE; Q05863; -.
DR   EnsemblFungi; YLR281C_mRNA; YLR281C; YLR281C.
DR   GeneID; 850987; -.
DR   KEGG; sce:YLR281C; -.
DR   SGD; S000004271; YLR281C.
DR   VEuPathDB; FungiDB:YLR281C; -.
DR   eggNOG; KOG2726; Eukaryota.
DR   HOGENOM; CLU_089470_4_0_1; -.
DR   InParanoid; Q05863; -.
DR   OMA; WEQQSKR; -.
DR   BioCyc; YEAST:G3O-32378-MON; -.
DR   PRO; PR:Q05863; -.
DR   Proteomes; UP000002311; Chromosome XII.
DR   RNAct; Q05863; protein.
DR   GO; GO:0005739; C:mitochondrion; IDA:SGD.
DR   GO; GO:0003747; F:translation release factor activity; IEA:InterPro.
DR   InterPro; IPR000352; Pep_chain_release_fac_I.
DR   InterPro; IPR045853; Pep_chain_release_fac_I_sf.
DR   Pfam; PF00472; RF-1; 1.
DR   SUPFAM; SSF75620; SSF75620; 1.
PE   1: Evidence at protein level;
KW   Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..17
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..155
FT                   /note="Uncharacterized peptide chain release factor-like
FT                   protein YLR281C, mitochondrial"
FT                   /id="PRO_0000247341"
FT   REGION          111..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        121..155
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   155 AA;  18197 MW;  DA2EDC596665C38D CRC64;
     MMRGASKRSI SSAAVLLIKK NKLPPRPKFT PEMEAQCTEK FLHGGRGPGG QKINKCNSKV
     QLRHEPTGIV VECQETRSRE QNRKLARLKL ARELAASYDT MPSREEALLQ WHRQQKRSQR
     RRSVAKYEQR EEAARVEKEE REARDREMVR ELFRR