ID   YL376_MIMIV             Reviewed;         199 AA.
AC   Q5UQW1;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Putative DNA-directed RNA polymerase subunit L376;
DE            EC=2.7.7.6;
GN   OrderedLocusNames=MIMI_L376;
OS   Acanthamoeba polyphaga mimivirus (APMV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Imitervirales; Mimiviridae; Mimivirus.
OX   NCBI_TaxID=212035;
OH   NCBI_TaxID=5757; Acanthamoeba polyphaga (Amoeba).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Rowbotham-Bradford;
RX   PubMed=15486256; DOI=10.1126/science.1101485;
RA   Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H.,
RA   La Scola B., Susan M., Claverie J.-M.;
RT   "The 1.2-megabase genome sequence of Mimivirus.";
RL   Science 306:1344-1350(2004).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], AND SUBCELLULAR
RP   LOCATION.
RX   PubMed=16971431; DOI=10.1128/jvi.00940-06;
RA   Renesto P., Abergel C., Decloquement P., Moinier D., Azza S., Ogata H.,
RA   Fourquet P., Gorvel J.-P., Claverie J.-M., Raoult D.;
RT   "Mimivirus giant particles incorporate a large fraction of anonymous and
RT   unique gene products.";
RL   J. Virol. 80:11678-11685(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6;
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:16971431}.
CC   -!- SIMILARITY: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit
CC       family. {ECO:0000305}.
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DR   EMBL; AY653733; AAV50645.1; -; Genomic_DNA.
DR   RefSeq; YP_003986881.1; NC_014649.1.
DR   SMR; Q5UQW1; -.
DR   GeneID; 9924997; -.
DR   KEGG; vg:9924997; -.
DR   Proteomes; UP000001134; Genome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   Gene3D; 2.40.50.140; -; 1.
DR   Gene3D; 3.30.1490.120; -; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR036898; RNA_pol_Rpb7-like_N_sf.
DR   InterPro; IPR045113; Rpb7-like.
DR   PANTHER; PTHR12709; PTHR12709; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF88798; SSF88798; 1.
PE   1: Evidence at protein level;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase; Virion.
FT   CHAIN           1..199
FT                   /note="Putative DNA-directed RNA polymerase subunit L376"
FT                   /id="PRO_0000253249"
SQ   SEQUENCE   199 AA;  22532 MW;  7CD53F807014D87E CRC64;
     MAQQSLYFQT KLEDKVSLLP SQMVGNMENY LLENLEAKVK DKVTEHGIVL KVNRIIEYDY
     GIISKNNFSG TAIYRVKYEC LICSPVKNLS IICLVENIVK GYIIAKNGPV IVAIPFNNID
     SDKFQLTNGN IVYKNNSNNI QKGDYVKVSI INIKTNLNEK KITTIAKLLD MATNDEIKSY
     DNDQLLIVNG DVDDEQEFI