YL455_YEAST
ID YL455_YEAST Reviewed; 304 AA.
AC Q06188; D6VZ89;
DT 25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=PWWP domain-containing protein YLR455W;
GN OrderedLocusNames=YLR455W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169871;
RA Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W.,
RA Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A.,
RA Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K.,
RA Heuss-Neitzel D., Hilbert H., Hilger F., Kleine K., Koetter P., Louis E.J.,
RA Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S.,
RA Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D.,
RA Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M.,
RA Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P.,
RA Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M.,
RA Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K.,
RA Zollner A., Hani J., Hoheisel J.D.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.";
RL Nature 387:87-90(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [4]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [5]
RP INDUCTION.
RX PubMed=16278933; DOI=10.1002/yea.1302;
RA de Lichtenberg U., Wernersson R., Jensen T.S., Nielsen H.B., Fausboell A.,
RA Schmidt P., Hansen F.B., Knudsen S., Brunak S.;
RT "New weakly expressed cell cycle-regulated genes in yeast.";
RL Yeast 22:1191-1201(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:14562095}.
CC -!- INDUCTION: During S phase of cell cycle. {ECO:0000269|PubMed:16278933}.
CC -!- MISCELLANEOUS: Present with 2610 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; U22383; AAB64719.1; -; Genomic_DNA.
DR EMBL; BK006945; DAA09755.1; -; Genomic_DNA.
DR PIR; S59414; S59414.
DR RefSeq; NP_013560.3; NM_001182343.3.
DR AlphaFoldDB; Q06188; -.
DR SMR; Q06188; -.
DR BioGRID; 31714; 86.
DR DIP; DIP-3853N; -.
DR IntAct; Q06188; 28.
DR MINT; Q06188; -.
DR STRING; 4932.YLR455W; -.
DR iPTMnet; Q06188; -.
DR MaxQB; Q06188; -.
DR PaxDb; Q06188; -.
DR PRIDE; Q06188; -.
DR EnsemblFungi; YLR455W_mRNA; YLR455W; YLR455W.
DR GeneID; 851177; -.
DR KEGG; sce:YLR455W; -.
DR SGD; S000004447; YLR455W.
DR VEuPathDB; FungiDB:YLR455W; -.
DR eggNOG; ENOG502QWCQ; Eukaryota.
DR HOGENOM; CLU_051401_0_0_1; -.
DR InParanoid; Q06188; -.
DR OMA; YYWEQPH; -.
DR BioCyc; YEAST:G3O-32508-MON; -.
DR PRO; PR:Q06188; -.
DR Proteomes; UP000002311; Chromosome XII.
DR RNAct; Q06188; protein.
DR GO; GO:0005829; C:cytosol; IDA:SGD.
DR GO; GO:0033100; C:NuA3 histone acetyltransferase complex; IDA:SGD.
DR GO; GO:1990468; C:NuA3b histone acetyltransferase complex; IDA:SGD.
DR GO; GO:0005634; C:nucleus; IDA:SGD.
DR GO; GO:0003682; F:chromatin binding; IDA:SGD.
DR GO; GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IGI:SGD.
DR CDD; cd05840; SPBC215_ISWI_like; 1.
DR InterPro; IPR035503; IOC4-like_PWWP.
DR InterPro; IPR000313; PWWP_dom.
DR Pfam; PF00855; PWWP; 1.
DR SMART; SM00293; PWWP; 1.
DR PROSITE; PS50812; PWWP; 1.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome.
FT CHAIN 1..304
FT /note="PWWP domain-containing protein YLR455W"
FT /id="PRO_0000247356"
FT DOMAIN 7..68
FT /note="PWWP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00162"
FT REGION 145..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..172
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..189
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 304 AA; 35508 MW; 4FDEF7A7AB69C96D CRC64;
MTKDIRTGDL VLCKVGSFPP WPAVVFPQRL LRNDVYRKRK SNCVAVCFFN DPTYYWEQPS
RLKELDQDSI HNFILEHSKN ANQRELVNAY KEAKNFDDFN VFLQEKFEEE NRLSDLKAFE
KSEGSKIVAG EDPFVGRTKV VNKRKKNSIS IKEDPEDNQK SNEEESKPNI KPSKKKRPTA
NSGGKSNSGN KKKVKLDYSR RVEISQLFRR RIQRNLIQRE TPPTEHEIKE THELLNRIYE
NSDTKRPFFD LKALRESKLH KLLKAIVNDP DLGEFHPLCK EILLSWADLI TELKKEKLQA
LPTP
