ID   YL720_MIMIV             Reviewed;         274 AA.
AC   Q5UNW7;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 2.
DT   02-JUN-2021, entry version 68.
DE   RecName: Full=Endonuclease 8-like L720;
DE   AltName: Full=Endonuclease VIII-like L720;
GN   OrderedLocusNames=MIMI_L720;
OS   Acanthamoeba polyphaga mimivirus (APMV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Imitervirales; Mimiviridae; Mimivirus.
OX   NCBI_TaxID=212035;
OH   NCBI_TaxID=5757; Acanthamoeba polyphaga (Amoeba).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rowbotham-Bradford;
RX   PubMed=15486256; DOI=10.1126/science.1101485;
RA   Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H.,
RA   La Scola B., Susan M., Claverie J.-M.;
RT   "The 1.2-megabase genome sequence of Mimivirus.";
RL   Science 306:1344-1350(2004).
CC   -!- SIMILARITY: Belongs to the FPG family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAV50980.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AY653733; AAV50980.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; YP_003987249.1; NC_014649.1.
DR   PDB; 4MB7; X-ray; 2.04 A; A=2-274.
DR   PDBsum; 4MB7; -.
DR   SMR; Q5UNW7; -.
DR   GeneID; 9925374; -.
DR   KEGG; vg:9925374; -.
DR   Proteomes; UP000001134; Genome.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0003906; F:DNA-(apurinic or apyrimidinic site) endonuclease activity; IEA:InterPro.
DR   GO; GO:0016799; F:hydrolase activity, hydrolyzing N-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   Gene3D; 3.20.190.10; -; 1.
DR   InterPro; IPR015886; DNA_glyclase/AP_lyase_DNA-bd.
DR   InterPro; IPR035937; MutM-like_N-ter.
DR   InterPro; IPR010979; Ribosomal_S13-like_H2TH.
DR   Pfam; PF06831; H2TH; 1.
DR   SMART; SM01232; H2TH; 1.
DR   SUPFAM; SSF46946; SSF46946; 1.
DR   SUPFAM; SSF81624; SSF81624; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..274
FT                   /note="Endonuclease 8-like L720"
FT                   /id="PRO_0000248636"
FT   ZN_FING         241..274
FT                   /note="FPG-type; degenerate"
FT   HELIX           6..14
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   HELIX           15..17
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   STRAND          21..27
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   HELIX           28..33
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   STRAND          41..48
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   STRAND          51..57
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   STRAND          64..79
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   STRAND          89..94
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   STRAND          99..110
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   STRAND          117..119
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   STRAND          124..126
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   HELIX           127..137
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   HELIX           138..140
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   HELIX           149..162
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   TURN            163..165
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   HELIX           168..172
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   TURN            175..177
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   HELIX           183..192
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   HELIX           201..203
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   HELIX           206..231
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   STRAND          255..259
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   TURN            260..263
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   STRAND          264..268
FT                   /evidence="ECO:0007829|PDB:4MB7"
FT   TURN            270..272
FT                   /evidence="ECO:0007829|PDB:4MB7"
SQ   SEQUENCE   274 AA;  32402 MW;  86F5F7A5D68D4491 CRC64;
     MVEAPRIRIT YEKIRHTKNH RIVSISGPSY KRMNVDLIDY IIRKWWFAGK YIYLMLISSN
     KPTYVIRTHM MMHGRILVGN QDSPTKRAFM IIQLDNDIVL RWYRSQITLL DPNCLAEIKT
     NYTICTTRQA IMDSIKLMKY DLSNNRFDYN LFQSHLKNGI NIHSSEIITD FLLDQEYFPG
     VGNILQQEAL YDCKILPLKK VQDIDEPMFD CLCNSLKKII DLLYESYKFR ESGKEFGPIL
     RIYRKSLCPL GHKTIRKKIG LRNRMTTWCP VCQL