ID   YL86_CAEEL              Reviewed;         325 AA.
AC   P34444; D1MN60; D1MN61; E1B6R2;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   22-FEB-2012, sequence version 3.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Uncharacterized protein F54C8.6;
GN   ORFNames=F54C8.6;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC   STRAIN=Bristol N2;
RX   PubMed=7906398; DOI=10.1038/368032a0;
RA   Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA   Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA   Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA   Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA   Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA   Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA   Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA   Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA   Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA   Wilkinson-Sproat J., Wohldman P.;
RT   "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT   elegans.";
RL   Nature 368:32-38(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=4;
CC       Name=b;
CC         IsoId=P34444-1; Sequence=Displayed;
CC       Name=a;
CC         IsoId=P34444-2; Sequence=VSP_042369;
CC       Name=c;
CC         IsoId=P34444-3; Sequence=VSP_042367;
CC       Name=d;
CC         IsoId=P34444-4; Sequence=VSP_042368;
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DR   EMBL; Z22178; CAA80158.2; -; Genomic_DNA.
DR   EMBL; Z22178; CBI63221.1; -; Genomic_DNA.
DR   EMBL; Z22178; CBI63222.1; -; Genomic_DNA.
DR   EMBL; Z22178; CBW48395.1; -; Genomic_DNA.
DR   PIR; B88555; B88555.
DR   RefSeq; NP_001254990.1; NM_001268061.1. [P34444-1]
DR   RefSeq; NP_001254991.1; NM_001268062.1. [P34444-2]
DR   RefSeq; NP_001254992.1; NM_001268063.1. [P34444-3]
DR   RefSeq; NP_001254993.1; NM_001268064.1. [P34444-4]
DR   AlphaFoldDB; P34444; -.
DR   EPD; P34444; -.
DR   PaxDb; P34444; -.
DR   PeptideAtlas; P34444; -.
DR   EnsemblMetazoa; F54C8.6a.1; F54C8.6a.1; WBGene00010039. [P34444-2]
DR   EnsemblMetazoa; F54C8.6a.2; F54C8.6a.2; WBGene00010039. [P34444-2]
DR   EnsemblMetazoa; F54C8.6b.1; F54C8.6b.1; WBGene00010039. [P34444-1]
DR   EnsemblMetazoa; F54C8.6c.1; F54C8.6c.1; WBGene00010039. [P34444-3]
DR   EnsemblMetazoa; F54C8.6d.1; F54C8.6d.1; WBGene00010039. [P34444-4]
DR   GeneID; 186224; -.
DR   KEGG; cel:CELE_F54C8.6; -.
DR   UCSC; F54C8.6; c. elegans. [P34444-1]
DR   CTD; 186224; -.
DR   WormBase; F54C8.6a; CE44342; WBGene00010039; -. [P34444-2]
DR   WormBase; F54C8.6b; CE44359; WBGene00010039; -. [P34444-1]
DR   WormBase; F54C8.6c; CE28832; WBGene00010039; -. [P34444-3]
DR   WormBase; F54C8.6d; CE45327; WBGene00010039; -. [P34444-4]
DR   eggNOG; ENOG502TFM6; Eukaryota.
DR   InParanoid; P34444; -.
DR   OMA; QFFHQII; -.
DR   OrthoDB; 1717483at2759; -.
DR   PRO; PR:P34444; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00010039; Expressed in pharyngeal muscle cell (C elegans) and 3 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Alternative splicing; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..325
FT                   /note="Uncharacterized protein F54C8.6"
FT                   /id="PRO_0000065359"
FT   TRANSMEM        159..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        292..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   VAR_SEQ         1..124
FT                   /note="Missing (in isoform d)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_042368"
FT   VAR_SEQ         1..60
FT                   /note="Missing (in isoform c)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_042367"
FT   VAR_SEQ         2..47
FT                   /note="SGRYEVQNRYSAYIEARRNYLEQSESEEDIEVRTILRRPQIYSRRT -> VS
FT                   SLTSVFRNRNQNPEKKSKDKKG (in isoform a)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_042369"
SQ   SEQUENCE   325 AA;  36947 MW;  F024C7F145E5EC49 CRC64;
     MSGRYEVQNR YSAYIEARRN YLEQSESEED IEVRTILRRP QIYSRRTVST SSEEQPTTPA
     MVLVPTVTIQ EAPKVVEIPT NGLPEPTPSS SVVQEIEILA PNEDEVKEEK PSDCTTCKKI
     ENFVMPYYES LKAKYQQFVV RISDPALHAT IRSEFAEYFP SVLLGFAIFF FGITFISFIK
     LLRGVSTQPS FFCRYFSGPF SPLFDALCEP DPYVLSEELP KVMSGLLDEM FITISEFFQT
     ISKGFTVFGT LFTAIWHGLS ENVFFGFHEL GENLGENINH LLHFVVQFFH QIIHLILSSI
     ATIAGAIAGV FTSVHDYLEP PQNVW