ID   YL87_SCHPO              Reviewed;         113 AA.
AC   Q9UTB1;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=HIG1 domain-containing protein C25B8.07c, mitochondrial;
GN   ORFNames=SPAC25B8.07c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00836, ECO:0000269|PubMed:16823372}; Multi-pass membrane
CC       protein {ECO:0000255|PROSITE-ProRule:PRU00836,
CC       ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329670; CAB61773.1; -; Genomic_DNA.
DR   PIR; T50194; T50194.
DR   RefSeq; NP_594467.1; NM_001019896.2.
DR   AlphaFoldDB; Q9UTB1; -.
DR   BioGRID; 279115; 4.
DR   STRING; 4896.SPAC25B8.07c.1; -.
DR   MaxQB; Q9UTB1; -.
DR   PaxDb; Q9UTB1; -.
DR   EnsemblFungi; SPAC25B8.07c.1; SPAC25B8.07c.1:pep; SPAC25B8.07c.
DR   GeneID; 2542662; -.
DR   KEGG; spo:SPAC25B8.07c; -.
DR   PomBase; SPAC25B8.07c; -.
DR   VEuPathDB; FungiDB:SPAC25B8.07c; -.
DR   eggNOG; KOG4431; Eukaryota.
DR   HOGENOM; CLU_2211472_0_0_1; -.
DR   InParanoid; Q9UTB1; -.
DR   OMA; FMKYRVL; -.
DR   PhylomeDB; Q9UTB1; -.
DR   PRO; PR:Q9UTB1; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0031305; C:integral component of mitochondrial inner membrane; ISO:PomBase.
DR   GO; GO:0005739; C:mitochondrion; HDA:PomBase.
DR   GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; ISO:PomBase.
DR   GO; GO:0097250; P:mitochondrial respirasome assembly; IBA:GO_Central.
DR   InterPro; IPR007667; Hypoxia_induced_domain.
DR   Pfam; PF04588; HIG_1_N; 1.
DR   PROSITE; PS51503; HIG1; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..113
FT                   /note="HIG1 domain-containing protein C25B8.07c,
FT                   mitochondrial"
FT                   /id="PRO_0000372339"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT   TRANSMEM        75..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT   DOMAIN          12..103
FT                   /note="HIG1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   113 AA;  12741 MW;  43B42F0BD1712EC1 CRC64;
     MSSKLPKKSE ENLELPTFPA SEESLSRSEK LKYVFVRNPF IPLGCLMTVG TFLASGYYIR
     RENHLMANKF MRYRVMSQGF TLAALAFSVL FIGPPRREAP SNSSGSINSE IKK