YL8B_SCHPO
ID YL8B_SCHPO Reviewed; 654 AA.
AC Q9UTA7;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Uncharacterized transcriptional regulatory protein C25B8.11;
GN ORFNames=SPAC25B8.11;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000255|PROSITE-ProRule:PRU00227, ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329670; CAB61777.1; -; Genomic_DNA.
DR PIR; T50198; T50198.
DR RefSeq; NP_594471.1; NM_001019900.2.
DR AlphaFoldDB; Q9UTA7; -.
DR BioGRID; 278071; 4.
DR STRING; 4896.SPAC25B8.11.1; -.
DR iPTMnet; Q9UTA7; -.
DR MaxQB; Q9UTA7; -.
DR PaxDb; Q9UTA7; -.
DR PRIDE; Q9UTA7; -.
DR EnsemblFungi; SPAC25B8.11.1; SPAC25B8.11.1:pep; SPAC25B8.11.
DR GeneID; 2541574; -.
DR KEGG; spo:SPAC25B8.11; -.
DR PomBase; SPAC25B8.11; -.
DR VEuPathDB; FungiDB:SPAC25B8.11; -.
DR eggNOG; ENOG502QQXX; Eukaryota.
DR HOGENOM; CLU_006632_1_1_1; -.
DR InParanoid; Q9UTA7; -.
DR OMA; FIADKWY; -.
DR PhylomeDB; Q9UTA7; -.
DR PRO; PR:Q9UTA7; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; NAS:PomBase.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; ISM:PomBase.
DR GO; GO:0008270; F:zinc ion binding; ISM:PomBase.
DR GO; GO:0001080; P:nitrogen catabolite activation of transcription from RNA polymerase II promoter; IBA:GO_Central.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR CDD; cd00067; GAL4; 1.
DR Gene3D; 4.10.240.10; -; 1.
DR InterPro; IPR007219; Transcription_factor_dom_fun.
DR InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR Pfam; PF04082; Fungal_trans; 1.
DR Pfam; PF00172; Zn_clus; 1.
DR SMART; SM00906; Fungal_trans; 1.
DR SMART; SM00066; GAL4; 1.
DR SUPFAM; SSF57701; SSF57701; 1.
DR PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm; DNA-binding; Metal-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation; Zinc.
FT CHAIN 1..654
FT /note="Uncharacterized transcriptional regulatory protein
FT C25B8.11"
FT /id="PRO_0000310389"
FT DNA_BIND 25..54
FT /note="Zn(2)-C6 fungal-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 63..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 654 AA; 74716 MW; 79412AE471D9FC0B CRC64;
MSNLILTPSN NGTERPYRSR KTRPCDNCRL RKSRCVVESI GNPCLLCTQL KIPCTYHLPP
IKRNKQKKQQ DSVSDDTPSE ATTTTNDDRD PKYNALGNNL DAVRGKVISP TQGSDARGPD
GRQVPLNLAG ITEMYHTSDD KFDKLGLDDS LNYPYVLGPT CDSDIDLIRE YFSFENGVCS
FDNMTVKYVS TSSKSPVMYI LDPAYENDRH SDFSRYDHAL HDLLSTYIDE ATGRTLVNLY
FSHVHPSYPI LHGPRFLLSY KNGSRNVPSI LLAALYSVAL TYWPSDSRSF GAPPLDQRKM
WTIVEEGLNF HFTQPRLSTI QAALLYLISR PLHNMYSLSS ILSRTTVLSQ LLGFNHDCTE
WKIPNEEKTI RKRIWWAIFI ADKWYSMYFG LATNIHEDDF VVPKIESDES LPLEITSSHS
FKTFLKMIEL SSLLQDILQD LFTVRALTRH SKNNRSISYQ IIGFFTRLNS IRPVEFTEPA
LGVASLKIQF DAVEILLWKT ALRFNLPDFQ SADDLFVCVE KSVSNFVQIT ANSSGDFFWP
YAGFHFSTLV SLLIRLHLDF HTNNTYGARA FSLLDAFVRH CITLHEAGFD FVEMAIRRSS
SLLKELGKDH PHLLALRDDI FNSNDSRGEE AYNHVPEQLF DPWNPHSWTF PKSD