CBL11_ARATH
ID CBL11_ARATH Reviewed; 668 AA.
AC Q9T045; Q67ZQ4;
DT 22-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2004, sequence version 2.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=COBRA-like protein 11 {ECO:0000303|PubMed:12376623};
DE AltName: Full=Protein POLLEN SPECIFIC GENE 4 {ECO:0000303|PubMed:25208507};
DE Flags: Precursor;
GN Name=COBL11 {ECO:0000303|PubMed:12376623};
GN Synonyms=PSG4 {ECO:0000303|PubMed:25208507};
GN OrderedLocusNames=At4g27110 {ECO:0000312|Araport:AT4G27110};
GN ORFNames=T24A18.60 {ECO:0000312|EMBL:CAB38841.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP TISSUE SPECIFICITY.
RX PubMed=12376623; DOI=10.1104/pp.007468;
RA Roudier F., Schindelman G., DeSalle R., Benfey P.N.;
RT "The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new
RT fellowship in expansion.";
RL Plant Physiol. 130:538-548(2002).
RN [5]
RP FUNCTION, AND SUBCELLULAR LOCATION.
RC STRAIN=cv. Columbia;
RX PubMed=23384085; DOI=10.1111/tpj.12139;
RA Li S., Ge F.-R., Xu M., Zhao X.-Y., Huang G.-Q., Zhou L.-Z., Wang J.-G.,
RA Kombrink A., McCormick S., Zhang X.S., Zhang Y.;
RT "Arabidopsis COBRA-LIKE 10, a GPI-anchored protein, mediates directional
RT growth of pollen tubes.";
RL Plant J. 74:486-497(2013).
RN [6]
RP TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia;
RX PubMed=25208507; DOI=10.1016/j.plaphy.2014.08.010;
RA Munoz-Strale D., Leon G.;
RT "Identification of two highly specific pollen promoters using
RT transcriptomic data.";
RL Plant Physiol. Biochem. 83:292-299(2014).
CC -!- FUNCTION: Involved in the deposition of apical pectin cap and cellulose
CC microfibrils in pollen tubes (PubMed:23384085). Implicated in pollen
CC tubes growth in the female transmitting tract of pistil and toward
CC micropyles, via the perception of ovule guidance cues
CC (PubMed:23384085). {ECO:0000269|PubMed:23384085}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:23384085};
CC Lipid-anchor, GPI-anchor {ECO:0000255}. Note=Localized at the apical
CC plasma membrane of pollen tubes (PubMed:23384085). In the cytoplasm,
CC observed in motile punctate vesicles (PubMed:23384085).
CC {ECO:0000269|PubMed:23384085}.
CC -!- TISSUE SPECIFICITY: Mostly expressed in flowers, stamen, anthers and
CC pollen, and, to a lower extent, possibly in roots, stems, leaves and
CC siliques. {ECO:0000269|PubMed:12376623, ECO:0000269|PubMed:25208507}.
CC -!- SIMILARITY: Belongs to the COBRA family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB38841.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CAB79566.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL035680; CAB38841.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL161566; CAB79566.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002687; AEE85302.1; -; Genomic_DNA.
DR EMBL; AK175703; BAD43466.1; -; mRNA.
DR EMBL; AK176063; BAD43826.1; -; mRNA.
DR PIR; T06041; T06041.
DR RefSeq; NP_567766.1; NM_118845.3.
DR AlphaFoldDB; Q9T045; -.
DR STRING; 3702.AT4G27110.1; -.
DR PaxDb; Q9T045; -.
DR PRIDE; Q9T045; -.
DR ProteomicsDB; 223929; -.
DR EnsemblPlants; AT4G27110.1; AT4G27110.1; AT4G27110.
DR GeneID; 828819; -.
DR Gramene; AT4G27110.1; AT4G27110.1; AT4G27110.
DR KEGG; ath:AT4G27110; -.
DR Araport; AT4G27110; -.
DR TAIR; locus:2136452; AT4G27110.
DR eggNOG; ENOG502QUPM; Eukaryota.
DR HOGENOM; CLU_420019_0_0_1; -.
DR InParanoid; Q9T045; -.
DR OMA; REYPFVK; -.
DR OrthoDB; 309219at2759; -.
DR PhylomeDB; Q9T045; -.
DR PRO; PR:Q9T045; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9T045; baseline and differential.
DR Genevisible; Q9T045; AT.
DR GO; GO:0031225; C:anchored component of membrane; TAS:TAIR.
DR GO; GO:0016324; C:apical plasma membrane; IDA:UniProtKB.
DR GO; GO:0031982; C:vesicle; IDA:UniProtKB.
DR GO; GO:0071555; P:cell wall organization; IMP:UniProtKB.
DR GO; GO:0010215; P:cellulose microfibril organization; IEA:InterPro.
DR GO; GO:0009860; P:pollen tube growth; IMP:UniProtKB.
DR GO; GO:0010183; P:pollen tube guidance; IMP:UniProtKB.
DR InterPro; IPR006918; COBRA_pln.
DR Pfam; PF04833; COBRA; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Glycoprotein; GPI-anchor; Lipoprotein; Membrane;
KW Reference proteome; Signal.
FT SIGNAL 1..29
FT /evidence="ECO:0000255"
FT CHAIN 30..636
FT /note="COBRA-like protein 11"
FT /id="PRO_0000005589"
FT PROPEP 637..668
FT /note="Removed in mature form"
FT /evidence="ECO:0000255"
FT /id="PRO_0000005590"
FT LIPID 636
FT /note="GPI-anchor amidated serine"
FT /evidence="ECO:0000255"
FT CARBOHYD 69
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 125
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 254
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 318
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 329
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 358
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 412
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 432
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 473
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 552
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 560
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 579
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 668 AA; 73849 MW; 51A842700FF8D4D8 CRC64;
MKKLRYVHLN LLLLLLPLIN LQFPTLSLAQ DYDEPKKDDT PPPGLARCNG VYMSYSSGGR
EKLYPRTTNA TAQAWSFKST AMIVNTGIEE VKGWQMFVGF HHREIIVSAT GAVSSDGDFP
VDATNGTTFI GSQNTDLKTS ILTAGDYTQI STNIEITGTV FGGKGTATPM PKSIKLTNDG
WQCPAATSKG GTMQVCCKRN PKFKAKEKVK TKFMPRQHGD LNIIYDVLQA YASSYMAQVT
IDNTSPLGRL DHWNLTWEWM RGEFIHSMRG AYAAEKNTLE CLSSKAGQFY GDLDFSQVAN
CQKKPIIKDL PAERKDDNVT GKLPFCCKNG TLLPTHMDPS KSKAIFQLQV YKVPPDQNRT
AFFPPRNWKI DGIVNPTYKC GPPIRVDATP FPDPSGLQAT TYAIASWQVI CNITKPKPQA
ARCCVSFSAF YNDSAIPCNT CACGCKDIDT DTCNANARQL LLPTDTLLVP FDNRTLKAKV
WAKQKHMAYP KKLPCPDNCG ISLNWHLNSD YGNGWSARVT LFNWGNNAVE DWFGALDLGK
AGLGYENIYS FNGSRVPPKN QTIFFQGLPG MNYLIGITNG TNPARDPQIP GKMQSVISFK
KKNLGSLNII GGDGFPKRVF FNGEECELPK YFPKKSSGMR LSGIRFLPSI LLAITTFHAI
TDRLLTGV
