ID   YLAC_BACSU              Reviewed;         173 AA.
AC   O07627; Q796J4;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   03-AUG-2022, entry version 122.
DE   RecName: Full=RNA polymerase sigma factor YlaC;
GN   Name=ylaC; OrderedLocusNames=BSU14730;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [2]
RP   FUNCTION.
RX   PubMed=16728958;
RA   Ryu H.-B., Shin I., Yim H.-S., Kang S.-O.;
RT   "YlaC is an extracytoplasmic function (ECF) sigma factor contributing to
RT   hydrogen peroxide resistance in Bacillus subtilis.";
RL   J. Microbiol. 44:206-216(2006).
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are then
CC       released. This sigma factor contributes to oxidative stress resistance.
CC       {ECO:0000269|PubMed:16728958}.
CC   -!- INDUCTION: By hydrogen peroxide.
CC   -!- MISCELLANEOUS: The interaction between YlaC and YlaD may be regulated
CC       by the redox state of YlaD.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000305}.
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DR   EMBL; Z97025; CAB09708.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB13346.1; -; Genomic_DNA.
DR   PIR; A69872; A69872.
DR   RefSeq; NP_389356.1; NC_000964.3.
DR   RefSeq; WP_003245485.1; NZ_JNCM01000035.1.
DR   AlphaFoldDB; O07627; -.
DR   SMR; O07627; -.
DR   STRING; 224308.BSU14730; -.
DR   PaxDb; O07627; -.
DR   PRIDE; O07627; -.
DR   EnsemblBacteria; CAB13346; CAB13346; BSU_14730.
DR   GeneID; 935973; -.
DR   KEGG; bsu:BSU14730; -.
DR   PATRIC; fig|224308.179.peg.1607; -.
DR   eggNOG; COG1595; Bacteria.
DR   InParanoid; O07627; -.
DR   OMA; EFQELSY; -.
DR   PhylomeDB; O07627; -.
DR   BioCyc; BSUB:BSU14730-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR039425; RNA_pol_sigma-70-like.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR014296; RNA_pol_sigma-M_bacilli.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR43133; PTHR43133; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF08281; Sigma70_r4_2; 1.
DR   SUPFAM; SSF88659; SSF88659; 1.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02950; SigM_subfam; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Reference proteome; Sigma factor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..173
FT                   /note="RNA polymerase sigma factor YlaC"
FT                   /id="PRO_0000248952"
SQ   SEQUENCE   173 AA;  20928 MW;  D1892DC81843DCBA CRC64;
     MKHRDSIEDL YRQYYQEILN YLFRRTHHLE TAKDLAQDTF VKALNGLASF RGHSSIRTWL
     YTIAHHTFIN WYRRDVKYQF TEISKNEGLT QTTYDQPEQY LSRTVKSETL RQELLKLKDQ
     HQSVLILREF QELSYEEIAE ILGWSLSKVN TTLHRARLEL KKNMTKSREE ERI