ID   YLAC_ECOLI              Reviewed;         156 AA.
AC   P0AAS0; P77523; Q2MBW9;
DT   11-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 2.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Inner membrane protein YlaC;
GN   Name=ylaC; OrderedLocusNames=b0458, JW5063;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RA   Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA   Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA   Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT   "Sequence of minutes 4-25 of Escherichia coli.";
RL   Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   TOPOLOGY [LARGE SCALE ANALYSIS].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=15919996; DOI=10.1126/science.1109730;
RA   Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT   "Global topology analysis of the Escherichia coli inner membrane
RT   proteome.";
RL   Science 308:1321-1323(2005).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB40213.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; U82664; AAB40213.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAC73560.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76237.1; -; Genomic_DNA.
DR   PIR; A64776; A64776.
DR   RefSeq; NP_414991.4; NC_000913.3.
DR   RefSeq; WP_000136192.1; NZ_STEB01000007.1.
DR   AlphaFoldDB; P0AAS0; -.
DR   BioGRID; 4261749; 2.
DR   STRING; 511145.b0458; -.
DR   jPOST; P0AAS0; -.
DR   PaxDb; P0AAS0; -.
DR   PRIDE; P0AAS0; -.
DR   EnsemblBacteria; AAC73560; AAC73560; b0458.
DR   EnsemblBacteria; BAE76237; BAE76237; BAE76237.
DR   GeneID; 66671240; -.
DR   GeneID; 948876; -.
DR   KEGG; ecj:JW5063; -.
DR   KEGG; eco:b0458; -.
DR   PATRIC; fig|1411691.4.peg.1818; -.
DR   EchoBASE; EB3989; -.
DR   eggNOG; ENOG50328KF; Bacteria.
DR   HOGENOM; CLU_134298_0_0_6; -.
DR   OMA; VDFYDVY; -.
DR   PhylomeDB; P0AAS0; -.
DR   BioCyc; EcoCyc:G6253-MON; -.
DR   PRO; PR:P0AAS0; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   InterPro; IPR019713; Memb_YlaC.
DR   Pfam; PF10777; YlaC; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..156
FT                   /note="Inner membrane protein YlaC"
FT                   /id="PRO_0000168634"
FT   TOPO_DOM        1..35
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        57..58
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        80..156
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   156 AA;  18267 MW;  4AF4BC6930818C81 CRC64;
     MTEIQRLLTE TIESLNTREK RDNKPRFSIS FIRKHPGLFI GMYVAFFATL AVMLQSETLS
     GSVWLLVVLF ILLNGFFFFD VYPRYRYEDI DVLDFRVCYN GEWYNTRFVP AALVEAILNS
     PRVADVHKEQ LQKMIVRKGE LSFYDIFTLA RAESTS