ID   YLAC_SHIFL              Reviewed;         156 AA.
AC   P0AAS2; P77523;
DT   11-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 2.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Inner membrane protein YlaC;
GN   Name=ylaC; OrderedLocusNames=SF0403, S0410;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
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DR   EMBL; AE005674; AAN42059.2; -; Genomic_DNA.
DR   EMBL; AE014073; AAP15936.1; -; Genomic_DNA.
DR   RefSeq; NP_706352.2; NC_004337.2.
DR   RefSeq; WP_000136192.1; NZ_WPGW01000015.1.
DR   AlphaFoldDB; P0AAS2; -.
DR   STRING; 198214.SF0403; -.
DR   EnsemblBacteria; AAN42059; AAN42059; SF0403.
DR   EnsemblBacteria; AAP15936; AAP15936; S0410.
DR   GeneID; 1027725; -.
DR   GeneID; 66671240; -.
DR   KEGG; sfl:SF0403; -.
DR   KEGG; sfx:S0410; -.
DR   PATRIC; fig|198214.7.peg.462; -.
DR   HOGENOM; CLU_134298_0_0_6; -.
DR   OrthoDB; 1426926at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR019713; Memb_YlaC.
DR   Pfam; PF10777; YlaC; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..156
FT                   /note="Inner membrane protein YlaC"
FT                   /id="PRO_0000168636"
FT   TOPO_DOM        1..35
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        57..58
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        80..156
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   156 AA;  18267 MW;  4AF4BC6930818C81 CRC64;
     MTEIQRLLTE TIESLNTREK RDNKPRFSIS FIRKHPGLFI GMYVAFFATL AVMLQSETLS
     GSVWLLVVLF ILLNGFFFFD VYPRYRYEDI DVLDFRVCYN GEWYNTRFVP AALVEAILNS
     PRVADVHKEQ LQKMIVRKGE LSFYDIFTLA RAESTS