ID   YLBL_BACSU              Reviewed;         341 AA.
AC   O34470; Q797T0;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 2.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Uncharacterized protein YlbL;
GN   Name=ylbL; OrderedLocusNames=BSU15050;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RA   Bertero M., Presecan E., Glaser P., Richou A., Danchin A.;
RT   "Bacillus subtilis chromosomal region downstream nprE.";
RL   Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   SEQUENCE REVISION TO C-TERMINUS.
RX   PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA   Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA   Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT   "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT   168 reference genome a decade later.";
RL   Microbiology 155:1758-1775(2009).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the peptidase S16 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01122}.
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DR   EMBL; Z98682; CAB11358.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB13378.2; -; Genomic_DNA.
DR   PIR; A69875; A69875.
DR   RefSeq; NP_389388.2; NC_000964.3.
DR   RefSeq; WP_003245451.1; NZ_JNCM01000035.1.
DR   RefSeq; WP_009967176.1; NZ_CM000487.1.
DR   PDB; 2KJP; NMR; -; A=128-210.
DR   PDBsum; 2KJP; -.
DR   AlphaFoldDB; O34470; -.
DR   BMRB; O34470; -.
DR   SMR; O34470; -.
DR   STRING; 224308.BSU15050; -.
DR   MEROPS; S16.012; -.
DR   PaxDb; O34470; -.
DR   EnsemblBacteria; CAB13378; CAB13378; BSU_15050.
DR   GeneID; 936755; -.
DR   KEGG; bsu:BSU15050; -.
DR   PATRIC; fig|224308.179.peg.1640; -.
DR   eggNOG; COG3480; Bacteria.
DR   InParanoid; O34470; -.
DR   OMA; TDHTFPF; -.
DR   PhylomeDB; O34470; -.
DR   BioCyc; BSUB:BSU15050-MON; -.
DR   EvolutionaryTrace; O34470; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0030163; P:protein catabolic process; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00986; PDZ_LON_protease; 1.
DR   Gene3D; 3.30.230.10; -; 1.
DR   InterPro; IPR039381; La_PDZ.
DR   InterPro; IPR008269; Lon_proteolytic.
DR   InterPro; IPR027065; Lon_Prtase.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR014721; Ribosomal_S5_D2-typ_fold_subgr.
DR   PANTHER; PTHR10046; PTHR10046; 1.
DR   Pfam; PF05362; Lon_C; 1.
DR   Pfam; PF13180; PDZ_2; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF50156; SSF50156; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   PROSITE; PS51786; LON_PROTEOLYTIC; 1.
DR   PROSITE; PS50106; PDZ; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cell membrane; Hydrolase; Membrane; Protease;
KW   Reference proteome; Serine protease; Transmembrane; Transmembrane helix.
FT   CHAIN           1..341
FT                   /note="Uncharacterized protein YlbL"
FT                   /id="PRO_0000360170"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          100..186
FT                   /note="PDZ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00143"
FT   DOMAIN          187..336
FT                   /note="Lon proteolytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01122"
FT   ACT_SITE        234
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01122"
FT   ACT_SITE        279
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01122"
FT   CONFLICT        340..341
FT                   /note="ST -> QPDSQVLFLYI (in Ref. 1; CAB11358)"
FT                   /evidence="ECO:0000305"
FT   STRAND          150..154
FT                   /evidence="ECO:0007829|PDB:2KJP"
FT   HELIX           162..169
FT                   /evidence="ECO:0007829|PDB:2KJP"
FT   STRAND          180..186
FT                   /evidence="ECO:0007829|PDB:2KJP"
SQ   SEQUENCE   341 AA;  37651 MW;  F9BB69A370758213 CRC64;
     MLRKKHFSWM LVILILIAVL SFIKLPYYIT KPGEATELAS LIKVEGGYPE KGSLSLMTVK
     VGPANPFTYV WAKMHPYYEI VPDESIKEEG ESDKEYMKRQ LQMMKSSQEN AVIAAYQKAG
     KKVSYSFNGI YASSVVENMP AKGKIEVGDK IISADGKNYQ SAEKLIDYIS SKKAGDKVTL
     KIEREEKEKR VTLTLKQFPD EPDRAGIGVS LYTDRNVKVE PDIDFEIENI GGPSAGLMMS
     LEIYNQLTKP DETKGYDIAG TGTIDVDGKV GPIGGIDQKV VAADKAGKDI FFAPNQNGAS
     NSDYKNAVKT AKDIDSNMKI VPVDTMQDAI DYLNKLKAKS T