ID   YLC1_CAEEL              Reviewed;         222 AA.
AC   Q8WQG1; Q18491;
DT   02-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=ER membrane protein complex subunit 7 homolog;
DE   Flags: Precursor;
GN   ORFNames=C35D10.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the EMC7 family. {ECO:0000305}.
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DR   EMBL; FO080789; CCD66774.1; -; Genomic_DNA.
DR   RefSeq; NP_001033353.1; NM_001038264.3.
DR   AlphaFoldDB; Q8WQG1; -.
DR   SMR; Q8WQG1; -.
DR   STRING; 6239.C35D10.1.2; -.
DR   EPD; Q8WQG1; -.
DR   PaxDb; Q8WQG1; -.
DR   PeptideAtlas; Q8WQG1; -.
DR   EnsemblMetazoa; C35D10.1.1; C35D10.1.1; WBGene00016439.
DR   GeneID; 175651; -.
DR   KEGG; cel:CELE_C35D10.1; -.
DR   UCSC; C35D10.1; c. elegans.
DR   CTD; 175651; -.
DR   WormBase; C35D10.1; CE29951; WBGene00016439; -.
DR   eggNOG; KOG3306; Eukaryota.
DR   GeneTree; ENSGT00390000017490; -.
DR   HOGENOM; CLU_073620_1_0_1; -.
DR   InParanoid; Q8WQG1; -.
DR   OMA; EMENMQM; -.
DR   OrthoDB; 1348328at2759; -.
DR   PhylomeDB; Q8WQG1; -.
DR   PRO; PR:Q8WQG1; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00016439; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0072546; C:EMC complex; IBA:GO_Central.
DR   InterPro; IPR039163; EMC7.
DR   InterPro; IPR019008; EMC7_beta_sandwich.
DR   PANTHER; PTHR13605; PTHR13605; 1.
DR   Pfam; PF09430; DUF2012; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255"
FT   CHAIN           17..222
FT                   /note="ER membrane protein complex subunit 7 homolog"
FT                   /id="PRO_0000065228"
FT   TOPO_DOM        17..145
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        146..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        167..222
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   222 AA;  24963 MW;  951F3132BD88F15C CRC64;
     MKSILLLFSL IVLGSATEEV SRTEQTSTLF SVEGEIALPS TRNCAKWSAG ARIHLNHGQY
     MGFVRQDCTF RVDFVPTGTY IVQIENTDFV FEPIRVDITS KGKMRARKLT ILQPNNVNTL
     PYPLRLSARG PARYFRKREE WRITDMLFSP MVLMLVVPLV VMLILPKMTA NDPELKKEME
     NMQMPKVDMP DVGEMMANFF GGSAPAKKKA VTGGSGSGQR RK