ID   YLL53_YEAS2             Reviewed;         152 AA.
AC   C7GNE2;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   13-OCT-2009, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Putative uncharacterized protein C1Q_01798;
GN   ORFNames=C1Q_01798;
OS   Saccharomyces cerevisiae (strain JAY291) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=574961;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JAY291;
RX   PubMed=19812109; DOI=10.1101/gr.091777.109;
RA   Argueso J.L., Carazzolle M.F., Mieczkowski P.A., Duarte F.M., Netto O.V.C.,
RA   Missawa S.K., Galzerani F., Costa G.G.L., Vidal R.O., Noronha M.F.,
RA   Dominska M., Andrietta M.G.S., Andrietta S.R., Cunha A.F., Gomes L.H.,
RA   Tavares F.C.A., Alcarde A.R., Dietrich F.S., McCusker J.H., Petes T.D.,
RA   Pereira G.A.G.;
RT   "Genome structure of a Saccharomyces cerevisiae strain widely used in
RT   bioethanol production.";
RL   Genome Res. 19:2258-2270(2009).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC       {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. This is the C-terminal
CC       part of aquaporin-2. A natural 11 bp deletion in position 109 leads to
CC       a frameshift, which disrupts the gene coding for this protein and
CC       produces two ORFs C1Q_01794 and C1Q_01798. A contiguous sequence for
CC       aquaporin-2 can be found in strain Sigma 1278B (AC P0CD89).
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ACFL01000073; EEU07687.1; -; Genomic_DNA.
DR   AlphaFoldDB; C7GNE2; -.
DR   SMR; C7GNE2; -.
DR   Proteomes; UP000008073; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015267; F:channel activity; IEA:InterPro.
DR   Gene3D; 1.20.1080.10; -; 1.
DR   InterPro; IPR023271; Aquaporin-like.
DR   InterPro; IPR034294; Aquaporin_transptr.
DR   InterPro; IPR000425; MIP.
DR   PANTHER; PTHR19139; PTHR19139; 1.
DR   Pfam; PF00230; MIP; 1.
DR   PRINTS; PR00783; MINTRINSICP.
DR   SUPFAM; SSF81338; SSF81338; 1.
PE   5: Uncertain;
KW   Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..152
FT                   /note="Putative uncharacterized protein C1Q_01798"
FT                   /id="PRO_0000391658"
FT   TOPO_DOM        1..5
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        27..38
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        60..65
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        66..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        87..110
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        132..152
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   MOTIF           92..94
FT                   /note="NPA"
SQ   SEQUENCE   152 AA;  16456 MW;  5E36E11629D1EF23 CRC64;
     MWFPQIIAGM AAGGAASAMT PGKVLFTNAL GLGCSRSRGL FLEMFGTAVL CLTVLMTAVE
     KRETNFMAAL PIGISLFMAH MALTGYTGTG VNPARSLGAA VAARYFPHYH WIYWISPLLG
     AFLAWSVWQL LQILDYTTYV NAEKAAGQKK ED