YLL53_YEAS7
ID YLL53_YEAS7 Reviewed; 152 AA.
AC A7A0K7;
DT 02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 11-SEP-2007, sequence version 1.
DT 25-MAY-2022, entry version 47.
DE RecName: Full=Putative uncharacterized protein SCY_3531;
GN ORFNames=SCY_3531;
OS Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=307796;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YJM789;
RX PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA Steinmetz L.M.;
RT "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT strain YJM789.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. This is the C-terminal
CC part of aquaporin-2. A natural 11 bp deletion in position 109 leads to
CC a frameshift, which disrupts the gene coding for this protein and
CC produces two ORFs SCY_3532 and SCY_3531. A contiguous sequence for
CC aquaporin-2 can be found in strain Sigma 1278B (AC P0CD89).
CC {ECO:0000305}.
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DR EMBL; AAFW02000167; EDN59498.1; -; Genomic_DNA.
DR AlphaFoldDB; A7A0K7; -.
DR SMR; A7A0K7; -.
DR EnsemblFungi; EDN59498; EDN59498; SCY_3531.
DR HOGENOM; CLU_127260_0_0_1; -.
DR Proteomes; UP000007060; Unassembled WGS sequence.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015267; F:channel activity; IEA:InterPro.
DR Gene3D; 1.20.1080.10; -; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR034294; Aquaporin_transptr.
DR InterPro; IPR000425; MIP.
DR PANTHER; PTHR19139; PTHR19139; 1.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; SSF81338; 1.
PE 5: Uncertain;
KW Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..152
FT /note="Putative uncharacterized protein SCY_3531"
FT /id="PRO_0000391659"
FT TOPO_DOM 1..5
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 27..38
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 60..65
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 66..86
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 87..110
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 111..131
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 132..152
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT MOTIF 92..94
FT /note="NPA"
SQ SEQUENCE 152 AA; 16490 MW; DCBCC19427D1012D CRC64;
MWFPQIIAGM AAGGAASAMT PGKVLFTNAL GLGCSRSRGL FLEMFGTAVL CFTVLMTAVE
KRETNFMAAL PIGISLFMAH MALTGYTGTG VNPARSLGAA VAARYFPHYH WIYWISPLLG
AFLAWSVWQL LQILDYTTYV NAEKAAGQKK ED
