YLL53_YEAS8
ID YLL53_YEAS8 Reviewed; 152 AA.
AC C8ZCS2;
DT 02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 03-NOV-2009, sequence version 1.
DT 25-MAY-2022, entry version 43.
DE RecName: Full=Putative uncharacterized protein EC1118_1L10_0100g;
GN ORFNames=EC1118_1L10_0100g;
OS Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's
OS yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=643680;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lalvin EC1118 / Prise de mousse;
RX PubMed=19805302; DOI=10.1073/pnas.0904673106;
RA Novo M., Bigey F., Beyne E., Galeote V., Gavory F., Mallet S., Cambon B.,
RA Legras J.-L., Wincker P., Casaregola S., Dequin S.;
RT "Eukaryote-to-eukaryote gene transfer events revealed by the genome
RT sequence of the wine yeast Saccharomyces cerevisiae EC1118.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:16333-16338(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. This is the C-terminal
CC part of aquaporin-2. A natural 11 bp deletion in position 109 leads to
CC a frameshift, which disrupts the gene coding for this protein and
CC produces two ORFs EC1118_1L10_0111g and EC1118_1L10_0100g. A contiguous
CC sequence for aquaporin-2 can be found in strain Sigma 1278B (AC
CC P0CD89). {ECO:0000305}.
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DR EMBL; FN393078; CAY81188.1; -; Genomic_DNA.
DR AlphaFoldDB; C8ZCS2; -.
DR SMR; C8ZCS2; -.
DR EnsemblFungi; CAY81188; CAY81188; EC1118_1L10_0100g.
DR HOGENOM; CLU_127260_0_0_1; -.
DR Proteomes; UP000000286; Chromosome XII, Scaffold EC1118_1L10.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015267; F:channel activity; IEA:InterPro.
DR Gene3D; 1.20.1080.10; -; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR034294; Aquaporin_transptr.
DR InterPro; IPR000425; MIP.
DR PANTHER; PTHR19139; PTHR19139; 1.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; SSF81338; 1.
PE 5: Uncertain;
KW Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..152
FT /note="Putative uncharacterized protein EC1118_1L10_0100g"
FT /id="PRO_0000391660"
FT TOPO_DOM 1..5
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 27..38
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 60..65
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 66..86
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 87..110
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 111..131
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 132..152
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT MOTIF 92..94
FT /note="NPA"
SQ SEQUENCE 152 AA; 16456 MW; 5E36E11629D1EF23 CRC64;
MWFPQIIAGM AAGGAASAMT PGKVLFTNAL GLGCSRSRGL FLEMFGTAVL CLTVLMTAVE
KRETNFMAAL PIGISLFMAH MALTGYTGTG VNPARSLGAA VAARYFPHYH WIYWISPLLG
AFLAWSVWQL LQILDYTTYV NAEKAAGQKK ED
