YLW5_SCHPO
ID YLW5_SCHPO Reviewed; 695 AA.
AC Q9UT10;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Uncharacterized GTP-binding protein P8A3.05;
GN ORFNames=SPAP8A3.05;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family.
CC {ECO:0000255|PROSITE-ProRule:PRU01059}.
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DR EMBL; CU329670; CAB55172.1; -; Genomic_DNA.
DR PIR; T39242; T39242.
DR RefSeq; NP_594944.1; NM_001020375.2.
DR AlphaFoldDB; Q9UT10; -.
DR SMR; Q9UT10; -.
DR BioGRID; 278189; 4.
DR STRING; 4896.SPAP8A3.05.1; -.
DR MaxQB; Q9UT10; -.
DR PaxDb; Q9UT10; -.
DR PRIDE; Q9UT10; -.
DR EnsemblFungi; SPAP8A3.05.1; SPAP8A3.05.1:pep; SPAP8A3.05.
DR GeneID; 2541693; -.
DR KEGG; spo:SPAP8A3.05; -.
DR PomBase; SPAP8A3.05; -.
DR VEuPathDB; FungiDB:SPAP8A3.05; -.
DR eggNOG; KOG0458; Eukaryota.
DR HOGENOM; CLU_399096_0_0_1; -.
DR OMA; FETFSHN; -.
DR PhylomeDB; Q9UT10; -.
DR PRO; PR:Q9UT10; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0005525; F:GTP binding; ISS:PomBase.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:PomBase.
DR GO; GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; ISO:PomBase.
DR GO; GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; ISO:PomBase.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm; GTP-binding; Nucleotide-binding; Nucleus; Reference proteome.
FT CHAIN 1..695
FT /note="Uncharacterized GTP-binding protein P8A3.05"
FT /id="PRO_0000363371"
FT DOMAIN 278..492
FT /note="tr-type G"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01059"
FT REGION 1..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 242..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 287..294
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 357..361
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 417..420
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
SQ SEQUENCE 695 AA; 77882 MW; 6579616F18E37A2C CRC64;
MSRLSQLLNS KKAKQKPPSE HPIGLSSILK QDSSSSSDSP NFFPSSSTND HQERDTINDT
NFVVPEKQKT SKLALLAAER KKLHSSFPST QQQPPKTEKE KEKEPIQAKH KKNVENDFLL
QRFRKVRIAE KKDSEQPSSH EIHLTDDDDK TTLQKQMVES DQLKKNPQEV KLAPPSSFAK
CLTGAKKRVF EDQIEIHLSK SSLLGFNAPS PDDIVLMAQS KSKSFQKHKR LDEQLLNSVK
SMKKVSQQLK PQKNTNDSNN DHTLLSQDQL IELSKLVKPR TKLLLLGPPK SGKKTLLSRL
FFQIGSFDPK TMQKCTVLNA KKESLSSVLK STKTKWYDFE TFSNSYSSTI IDFPLGIFTT
NASSRDNFLK HSSLFQVMNT AIFTIDCLNP LEGLDGISSI LQLMNGLSIS SYMFAITKMD
EIEWDENKFI NLVNSIQSFL KESCGIIEKS KFIPISGLKG TNLTSISQEK LSQWYKSDTL
LGKIDKEADT NHGTWNFLLN LPLSLTISHI TPLPENQSHI YCSIHSGMLQ DSQKLYVGTG
RLETQITGLS SDENPKGFNV AGDMIQAKIP TLPNLCPGIL IADSIDAFTS SKTAYVNATW
FHGSLEKGKS MHVIALFGCH AVLTKLYCFT DSQEKAPNAI GNDLERNRTS LVKIELENAF
PLVKESYINT LSRVLFVSEK WNSLIAFGTV LSLHD
