YLY6_SCHPO
ID YLY6_SCHPO Reviewed; 184 AA.
AC Q9P7P9;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 84.
DE RecName: Full=Uncharacterized isomerase C186.06;
DE EC=5.1.-.-;
GN ORFNames=SPAC186.06;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP IDENTIFICATION OF PROBABLE ERRORS IN GENOMIC SEQUENCE.
RX PubMed=21270388; DOI=10.1534/genetics.110.123497;
RA Bitton D.A., Wood V., Scutt P.J., Grallert A., Yates T., Smith D.L.,
RA Hagan I.M., Miller C.J.;
RT "Augmented annotation of the Schizosaccharomyces pombe genome reveals
RT additional genes required for growth and viability.";
RL Genetics 187:1207-1217(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
CC -!- MISCELLANEOUS: Sequence homology predicts an N-terminally extended
CC version of this protein. However, this extension introduces 2
CC frameshifts, making it unlikely that this gene is correctly translated
CC or that there are errors in the genomic sequence.
CC -!- SIMILARITY: Belongs to the PhzF family. {ECO:0000305}.
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DR EMBL; CU329670; CAB75870.1; -; Genomic_DNA.
DR PIR; T50133; T50133.
DR RefSeq; NP_595024.1; NM_001020454.2.
DR AlphaFoldDB; Q9P7P9; -.
DR SMR; Q9P7P9; -.
DR BioGRID; 279049; 3.
DR STRING; 4896.SPAC186.06.1; -.
DR PaxDb; Q9P7P9; -.
DR EnsemblFungi; SPAC186.06.1; SPAC186.06.1:pep; SPAC186.06.
DR GeneID; 2542595; -.
DR KEGG; spo:SPAC186.06; -.
DR PomBase; SPAC186.06; -.
DR VEuPathDB; FungiDB:SPAC186.06; -.
DR eggNOG; KOG3033; Eukaryota.
DR HOGENOM; CLU_1469040_0_0_1; -.
DR InParanoid; Q9P7P9; -.
DR PhylomeDB; Q9P7P9; -.
DR PRO; PR:Q9P7P9; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0016853; F:isomerase activity; IBA:GO_Central.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR InterPro; IPR003719; Phenazine_PhzF.
DR PANTHER; PTHR13774; PTHR13774; 1.
DR Pfam; PF02567; PhzC-PhzF; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Isomerase; Nucleus; Reference proteome.
FT CHAIN 1..184
FT /note="Uncharacterized isomerase C186.06"
FT /id="PRO_0000317237"
SQ SEQUENCE 184 AA; 19627 MW; F70BDE6FF2BCFBCB CRC64;
MSIKLGYLFK LPSYKTSSIS PEVIVDLEKF LNLCEGSCSQ CNTPFCVDVG PRNAIIQLPN
GADVLNLNPN FQAIFECCSK NSLTGVQIFG MYNDGTYELR SFCPVHGVNE DPANGSGAGS
VGVFFALNNP SIISSDFAHL LFNQGKILGR NALIRVAIKL SANGLYDIHV GGGSKICISG
TAEI