ID   YM04_SCHPO              Reviewed;         288 AA.
AC   Q9HGP8;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=UPF0494 membrane protein C212.04c;
GN   ORFNames=SPAC212.04c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1] {ECO:0000312|EMBL:CAC05738.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2] {ECO:0000305}
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
CC       Endoplasmic reticulum {ECO:0000269|PubMed:16823372}. Membrane
CC       {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the UPF0494 family. {ECO:0000305}.
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DR   EMBL; CU329670; CAC05738.1; -; Genomic_DNA.
DR   RefSeq; NP_595038.1; NM_001018170.2.
DR   AlphaFoldDB; Q9HGP8; -.
DR   SMR; Q9HGP8; -.
DR   BioGRID; 278401; 28.
DR   STRING; 4896.SPAC212.04c.1; -.
DR   PaxDb; Q9HGP8; -.
DR   EnsemblFungi; SPAC212.04c.1; SPAC212.04c.1:pep; SPAC212.04c.
DR   GeneID; 2541911; -.
DR   KEGG; spo:SPAC212.04c; -.
DR   PomBase; SPAC212.04c; -.
DR   VEuPathDB; FungiDB:SPAC212.04c; -.
DR   HOGENOM; CLU_097271_0_0_1; -.
DR   OMA; WIGENQS; -.
DR   PhylomeDB; Q9HGP8; -.
DR   PRO; PR:Q9HGP8; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR009340; DUF999.
DR   Pfam; PF06198; DUF999; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Endoplasmic reticulum; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..288
FT                   /note="UPF0494 membrane protein C212.04c"
FT                   /id="PRO_0000306284"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        174..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        198..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   288 AA;  32290 MW;  FE79413D3F2213AE CRC64;
     MSNPESLKKQ VEPPGYNELF MVEDVCNVDL EQGLDLCKPE KVNKQSQRSR QSRQSLFTNT
     IKPQKDKMNI KTNKIKEFLN DLFTEFSKFH NSYYPNGRIS TQDKSRWVLL IIWSIITILT
     IDKKFKIKES YLEWIGENQS HSEIWGPIVI YVGLFILLLS AFNYCSKLII KALPLISMVI
     AWVGVVIAAF SVIITATIAG VIAAFSVIIT ATIAGVIAAM VGILYFGHWL VYKILILAFG
     FKIVTSGDVC VSNTLPTHNG ETALHSDATV GSDIEQIELQ NMPTPVKK