YM122_YEAST
ID YM122_YEAST Reviewed; 84 AA.
AC Q3E842; D6VZU5;
DT 25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Uncharacterized endoplasmic reticulum membrane protein YMR122W-A;
GN OrderedLocusNames=YMR122W-A;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169872;
RA Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T.,
RA Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K.,
RA Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P.,
RA Skelton J., Walsh S.V., Whitehead S., Barrell B.G.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.";
RL Nature 387:90-93(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP GENOME REANNOTATION.
RX PubMed=9358174; DOI=10.1093/nar/25.22.4619;
RA Olivas W.M., Muhlrad D., Parker R.;
RT "Analysis of the yeast genome: identification of new non-coding and small
RT ORF-containing RNAs.";
RL Nucleic Acids Res. 25:4619-4625(1997).
RN [4]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [5]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305};
CC Single-pass membrane protein {ECO:0000305}.
CC -!- MISCELLANEOUS: Present with 49500 molecules/cell in log phase SD
CC medium. {ECO:0000269|PubMed:14562106}.
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DR EMBL; Z49273; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BK006946; DAA10019.1; -; Genomic_DNA.
DR RefSeq; NP_061493.1; NM_001184445.1.
DR AlphaFoldDB; Q3E842; -.
DR BioGRID; 35299; 43.
DR DIP; DIP-62124N; -.
DR STRING; 4932.YMR122W-A; -.
DR iPTMnet; Q3E842; -.
DR MaxQB; Q3E842; -.
DR PaxDb; Q3E842; -.
DR PRIDE; Q3E842; -.
DR EnsemblFungi; YMR122W-A_mRNA; YMR122W-A; YMR122W-A.
DR GeneID; 855152; -.
DR KEGG; sce:YMR122W-A; -.
DR SGD; S000007524; YMR122W-A.
DR VEuPathDB; FungiDB:YMR122W-A; -.
DR HOGENOM; CLU_162197_0_0_1; -.
DR InParanoid; Q3E842; -.
DR OMA; PLSWKYG; -.
DR BioCyc; YEAST:G3O-33022-MON; -.
DR PRO; PR:Q3E842; -.
DR Proteomes; UP000002311; Chromosome XIII.
DR RNAct; Q3E842; protein.
DR GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:SGD.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Endoplasmic reticulum; Glycoprotein; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..84
FT /note="Uncharacterized endoplasmic reticulum membrane
FT protein YMR122W-A"
FT /id="PRO_0000247787"
FT TRANSMEM 66..83
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 34..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 45
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 84 AA; 7981 MW; 7B5FFAEA2618ADBB CRC64;
MASSTSTSAS ASSSIKTNSA LVSNNVVAAS SVSATSTASS SAAKNTTSSS KNAAPGMVAN
PVSSKYGIIM AAFAAVSFVL GTGI
