ID   YM59_YEAST              Reviewed;         457 AA.
AC   Q03648; D6W034;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 137.
DE   RecName: Full=Uncharacterized protein YMR209C;
GN   OrderedLocusNames=YMR209C; ORFNames=YM8261.03C;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169872;
RA   Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T.,
RA   Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K.,
RA   Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P.,
RA   Skelton J., Walsh S.V., Whitehead S., Barrell B.G.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.";
RL   Nature 387:90-93(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
RN   [4]
RP   LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX   PubMed=14562106; DOI=10.1038/nature02046;
RA   Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA   O'Shea E.K., Weissman J.S.;
RT   "Global analysis of protein expression in yeast.";
RL   Nature 425:737-741(2003).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- MISCELLANEOUS: Present with 981 molecules/cell in log phase SD medium.
CC       {ECO:0000269|PubMed:14562106}.
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DR   EMBL; Z49809; CAA89924.1; -; Genomic_DNA.
DR   EMBL; AY692616; AAT92635.1; -; Genomic_DNA.
DR   EMBL; BK006946; DAA10108.1; -; Genomic_DNA.
DR   PIR; S55091; S55091.
DR   RefSeq; NP_013936.1; NM_001182716.1.
DR   AlphaFoldDB; Q03648; -.
DR   SMR; Q03648; -.
DR   BioGRID; 35387; 42.
DR   DIP; DIP-4412N; -.
DR   IntAct; Q03648; 3.
DR   STRING; 4932.YMR209C; -.
DR   iPTMnet; Q03648; -.
DR   MaxQB; Q03648; -.
DR   PaxDb; Q03648; -.
DR   PRIDE; Q03648; -.
DR   EnsemblFungi; YMR209C_mRNA; YMR209C; YMR209C.
DR   GeneID; 855249; -.
DR   KEGG; sce:YMR209C; -.
DR   SGD; S000004822; YMR209C.
DR   VEuPathDB; FungiDB:YMR209C; -.
DR   eggNOG; KOG2798; Eukaryota.
DR   GeneTree; ENSGT00390000005323; -.
DR   HOGENOM; CLU_030612_3_0_1; -.
DR   InParanoid; Q03648; -.
DR   OMA; SMWQGYY; -.
DR   BioCyc; YEAST:G3O-32892-MON; -.
DR   ChiTaRS; YMR209C; yeast.
DR   PRO; PR:Q03648; -.
DR   Proteomes; UP000002311; Chromosome XIII.
DR   RNAct; Q03648; protein.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; ISM:SGD.
DR   InterPro; IPR012901; CARME.
DR   InterPro; IPR016853; S-AdoMet-bd_YMR209C_prd.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR12303; PTHR12303; 1.
DR   Pfam; PF07942; N2227; 1.
DR   PIRSF; PIRSF027174; SAM_bd_YMR209C_prd; 1.
DR   SMART; SM01296; N2227; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   1: Evidence at protein level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..457
FT                   /note="Uncharacterized protein YMR209C"
FT                   /id="PRO_0000203330"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        250..270
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   457 AA;  52246 MW;  B68737D1E58176E3 CRC64;
     MVSSLASNII LALVVVLMTL LRQNKPLQRW FVSYVEKLLS RKSNLAQKVS VLSPSLKLVD
     VEKSISADQS NLSKINYQIP TLPDLTGNLI RLHEYRARGE GYNGLLFRRA RQLNGISEDQ
     LQKLGYFTKL MKNNEGIREN ARVIDKIIEF TLGKLIHSNE HDEEFTEEIE KICAEHGYKI
     KDGHLIQLNP DFVFPIVSSR GSQSVVHEAL AHLCRDFSSY YSVERDPLQN FIISRINHHV
     ISAGDMKEKI LIVTPGAGVG GLSHTLATTF PKIQVDSIEL SALMYICNLF ALEYKHDVKI
     RPFVQQYSCQ TVFDNQLRSL SADLSKVGHR SNLDPLWGDF TRYSPISKDY DKIIICSAYF
     IDTAENMFEY LSSIEALKKY CKELHWVNVG PLKYGTKPLV QFTGDELSRL RKIRGWKDLV
     EEYEVDSSKG LNGYLTDYES MYQGYYGLLK FHSVFES