ID   CBL_KLEAE               Reviewed;         316 AA.
AC   Q08598;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=HTH-type transcriptional regulator cbl;
GN   Name=cbl;
OS   Klebsiella aerogenes (Enterobacter aerogenes).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=548;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=W70 / KC1043;
RX   PubMed=8458853; DOI=10.1128/jb.175.7.2107-2115.1993;
RA   Schwacha A., Bender R.A.;
RT   "The nac (nitrogen assimilation control) gene from Klebsiella aerogenes.";
RL   J. Bacteriol. 175:2107-2115(1993).
CC   -!- FUNCTION: May be an accessory regulatory protein within the cys
CC       regulon.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; L01114; AAA18174.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q08598; -.
DR   SMR; Q08598; -.
DR   STRING; 548.EAG7_00768; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..316
FT                   /note="HTH-type transcriptional regulator cbl"
FT                   /id="PRO_0000105603"
FT   DOMAIN          1..59
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        19..38
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   316 AA;  35703 MW;  17578BD9F50ECEA7 CRC64;
     MNFQQLKIIR EAARQDYNLT EVANMLYTSQ SGVSRHIREL EEELGIEIFI RRGKRLLGMT
     EPGKALLSIA ERILNEASNV RRLADLFTND ASGVLTIATT HTQARYSLPP VIKAFRELFS
     DVRVELVQGT PQEIEALLHN GGADIGIASE RLSNDPTLAA FPWFRWHHSL LVPKDHPLTQ
     VSPLTLEAIA RWPLITYRQG ITGRSRIDEA FNRKGLMPDI VLSAQDSDVI KTYVELGLGV
     GLVAEQSGDA READTFTRLD TRHLFDANTV WLGLKRGQLQ RNYVWRFIEL CNAGLSLDEI
     KRQAMEPEEV AIDYQI