YM91_YEAST
ID YM91_YEAST Reviewed; 317 AA.
AC Q04867; D6W0D7;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 03-AUG-2022, entry version 146.
DE RecName: Full=Putative methyltransferase YMR310C {ECO:0000305};
DE EC=2.1.1.- {ECO:0000305};
GN OrderedLocusNames=YMR310C {ECO:0000312|SGD:S000004927};
GN ORFNames=YM9924.02C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169872;
RA Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T.,
RA Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K.,
RA Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P.,
RA Skelton J., Walsh S.V., Whitehead S., Barrell B.G.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.";
RL Nature 387:90-93(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [4]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-190, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=18407956; DOI=10.1074/mcp.m700468-mcp200;
RA Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
RT "A multidimensional chromatography technology for in-depth phosphoproteome
RT analysis.";
RL Mol. Cell. Proteomics 7:1389-1396(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:14562095}.
CC -!- MISCELLANEOUS: Present with 2540 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: Belongs to the class IV-like SAM-binding methyltransferase
CC superfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; Z54141; CAA90828.1; -; Genomic_DNA.
DR EMBL; BK006946; DAA10211.1; -; Genomic_DNA.
DR PIR; S59303; S59303.
DR RefSeq; NP_014041.1; NM_001182821.1.
DR AlphaFoldDB; Q04867; -.
DR SMR; Q04867; -.
DR BioGRID; 35490; 95.
DR DIP; DIP-5337N; -.
DR IntAct; Q04867; 12.
DR MINT; Q04867; -.
DR STRING; 4932.YMR310C; -.
DR iPTMnet; Q04867; -.
DR MaxQB; Q04867; -.
DR PaxDb; Q04867; -.
DR PRIDE; Q04867; -.
DR EnsemblFungi; YMR310C_mRNA; YMR310C; YMR310C.
DR GeneID; 855358; -.
DR KEGG; sce:YMR310C; -.
DR SGD; S000004927; YMR310C.
DR VEuPathDB; FungiDB:YMR310C; -.
DR eggNOG; KOG3925; Eukaryota.
DR GeneTree; ENSGT00390000016537; -.
DR HOGENOM; CLU_061859_0_0_1; -.
DR InParanoid; Q04867; -.
DR OMA; YGYHVRI; -.
DR BioCyc; YEAST:G3O-32974-MON; -.
DR PRO; PR:Q04867; -.
DR Proteomes; UP000002311; Chromosome XIII.
DR RNAct; Q04867; protein.
DR GO; GO:0005634; C:nucleus; HDA:SGD.
DR GO; GO:0008168; F:methyltransferase activity; ISS:SGD.
DR GO; GO:0032259; P:methylation; IC:SGD.
DR CDD; cd18086; HsC9orf114-like; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR003750; Put_MeTrfase.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR PANTHER; PTHR12150; PTHR12150; 1.
DR Pfam; PF02598; Methyltrn_RNA_3; 1.
DR SUPFAM; SSF75217; SSF75217; 1.
PE 1: Evidence at protein level;
KW Methyltransferase; Nucleus; Phosphoprotein; Reference proteome;
KW Transferase.
FT CHAIN 1..317
FT /note="Putative methyltransferase YMR310C"
FT /id="PRO_0000203354"
FT MOD_RES 190
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:18407956"
SQ SEQUENCE 317 AA; 35852 MW; 42CA4DD7010D5ADF CRC64;
MSSTRKFKKV EKPLSQTRHY SLCIPTTLVS DCRNLSQITH KVYQVAKFAS LFNVSEVVIL
EDNSQVDATK KKISTAKLIL ALLQYFVTPP YLRNTVFNEK FRPYLTAASK LPRLSTLPFT
RYQKQDHGRY REGLTIKMQK PTLARKKIGK VFKQTKYINI GKSKALALQS QLVPINARVT
IDTITRKIVS PQEAYGDFTG LDSQYGYYTR IASSFTDLFM KGPLKEGYTQ SVYVPLTTRD
TSIPELSSLP TAETNPHILL VFSTWDTLAR AFKLDQDQFV DCQGPQEFFD AQLPCPVSNS
DVADAIPMTL TTLSTVF
