ID   YMCE_ECOLI              Reviewed;          76 AA.
AC   P0AAA5; P52634;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Uncharacterized protein YmcE;
GN   Name=ymcE; Synonyms=sfa; OrderedLocusNames=b0991, JW0975;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=8808925; DOI=10.1128/jb.178.18.5382-5387.1996;
RA   Rock C.O., Tsay J.-T., Heath R., Jackowski S.;
RT   "Increased unsaturated fatty acid production associated with a suppressor
RT   of the fabA6(Ts) mutation in Escherichia coli.";
RL   J. Bacteriol. 178:5382-5387(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA   Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA   Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA   Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA   Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA   Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA   Horiuchi T.;
RT   "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 12.7-28.0 min region on the linkage map.";
RL   DNA Res. 3:137-155(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   SHOWS THAT IT IS NOT A SUPPRESSOR OF FABA6(TS) MUTANTS.
RX   PubMed=11544213; DOI=10.1128/jb.183.19.5523-5528.2001;
RA   Sugai R., Shimizu H., Nishiyama K., Tokuda H.;
RT   "Overexpression of yccL (gnsA) and ydfY (gnsB) increases levels of
RT   unsaturated fatty acids and suppresses both the temperature-sensitive fabA6
RT   mutation and cold-sensitive secG null mutation of Escherichia coli.";
RL   J. Bacteriol. 183:5523-5528(2001).
RN   [6]
RP   INDUCTION BY COLD SHOCK.
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=14527658; DOI=10.1016/s0923-2508(03)00167-0;
RA   Polissi A., De Laurentis W., Zangrossi S., Briani F., Longhi V., Pesole G.,
RA   Deho G.;
RT   "Changes in Escherichia coli transcriptome during acclimatization at low
RT   temperature.";
RL   Res. Microbiol. 154:573-580(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- INDUCTION: Transiently induced by cold shock in a PNPase-dependent
CC       fashion. {ECO:0000269|PubMed:14527658}.
CC   -!- CAUTION: Was originally thought to suppress the temperature-sensitive
CC       growth phenotype of fabA6(Ts) mutants. {ECO:0000305|PubMed:8808925}.
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DR   EMBL; U38541; AAC44390.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC74076.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA35757.1; -; Genomic_DNA.
DR   PIR; E64840; E64840.
DR   RefSeq; NP_415511.1; NC_000913.3.
DR   RefSeq; WP_001309400.1; NZ_SSZK01000002.1.
DR   AlphaFoldDB; P0AAA5; -.
DR   BioGRID; 4260048; 6.
DR   STRING; 511145.b0991; -.
DR   PaxDb; P0AAA5; -.
DR   PRIDE; P0AAA5; -.
DR   EnsemblBacteria; AAC74076; AAC74076; b0991.
DR   EnsemblBacteria; BAA35757; BAA35757; BAA35757.
DR   GeneID; 946951; -.
DR   KEGG; ecj:JW0975; -.
DR   KEGG; eco:b0991; -.
DR   PATRIC; fig|83333.103.peg.1773; -.
DR   EchoBASE; EB3021; -.
DR   eggNOG; ENOG5033ZMW; Bacteria.
DR   HOGENOM; CLU_2478691_0_0_6; -.
DR   OMA; REMAYNI; -.
DR   BioCyc; EcoCyc:G6512-MON; -.
DR   PRO; PR:P0AAA5; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR031853; YmcE_antitoxin.
DR   Pfam; PF15939; YmcE_antitoxin; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..76
FT                   /note="Uncharacterized protein YmcE"
FT                   /id="PRO_0000097707"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   76 AA;  8727 MW;  0EF0A35DBB9BABFF CRC64;
     MRRWISQNNI RLPRGAFFIS ALFFFNAVCI VSDNLLIIES FGEMAYNISY LTRVPGTNTL
     LACCCLLRPE EVNSEY