YMF19_ARATH
ID YMF19_ARATH Reviewed; 158 AA.
AC P93303; Q4PL89;
DT 01-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1997, sequence version 1.
DT 03-AUG-2022, entry version 153.
DE RecName: Full=ATP synthase protein YMF19;
DE EC=7.1.2.2;
DE AltName: Full=Mitochondrial protein YMF19;
GN Name=YMF19; OrderedLocusNames=AtMg00480 {ECO:0000312|Araport:ATMG00480};
GN and
GN OrderedLocusNames=At2g07707 {ECO:0000312|Araport:AT2G07707};
OS Arabidopsis thaliana (Mouse-ear cress).
OG Mitochondrion.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. C24;
RX PubMed=8988169; DOI=10.1038/ng0197-57;
RA Unseld M., Marienfeld J.R., Brandt P., Brennicke A.;
RT "The mitochondrial genome of Arabidopsis thaliana contains 57 genes in
RT 366,924 nucleotides.";
RL Nat. Genet. 15:57-61(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (AT2G07707).
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION (AT2G07707).
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (AT2G07707).
RC STRAIN=cv. Columbia;
RX PubMed=16244158; DOI=10.1104/pp.105.063479;
RA Xiao Y.-L., Smith S.R., Ishmael N., Redman J.C., Kumar N., Monaghan E.L.,
RA Ayele M., Haas B.J., Wu H.C., Town C.D.;
RT "Analysis of the cDNAs of hypothetical genes on Arabidopsis chromosome 2
RT reveals numerous transcript variants.";
RL Plant Physiol. 139:1323-1337(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (AT2G07707).
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Quinitio C., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBUNIT.
RX PubMed=12681508; DOI=10.1016/s0014-5793(03)00264-3;
RA Heazlewood J.L., Whelan J., Millar A.H.;
RT "The products of the mitochondrial orf25 and orfB genes are F(0) components
RT in the plant F(1)F(0) ATP synthase.";
RL FEBS Lett. 540:201-205(2003).
RN [7]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION [LARGE SCALE
RP ANALYSIS].
RC STRAIN=cv. Landsberg erecta;
RX PubMed=14671022; DOI=10.1105/tpc.016055;
RA Heazlewood J.L., Tonti-Filippini J.S., Gout A.M., Day D.A., Whelan J.,
RA Millar A.H.;
RT "Experimental analysis of the Arabidopsis mitochondrial proteome highlights
RT signaling and regulatory components, provides assessment of targeting
RT prediction programs, and indicates plant-specific mitochondrial proteins.";
RL Plant Cell 16:241-256(2004).
CC -!- FUNCTION: This is one of the chains of the nonenzymatic component
CC (CF(0) subunit) of the mitochondrial ATPase complex.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate;
CC Xref=Rhea:RHEA:57720, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.1.2.2;
CC -!- SUBUNIT: F-type ATPases have 2 components, CF(1) - the catalytic core
CC - and CF(0) - the membrane proton channel. CF(1) has five subunits:
CC alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main
CC subunits: a, b and c (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane
CC {ECO:0000269|PubMed:14671022}; Single-pass membrane protein
CC {ECO:0000269|PubMed:14671022}.
CC -!- MISCELLANEOUS: A stretch of 270 kb of the mitochondrial genome is
CC duplicated within the centromere of chromosome 2 resulting in the
CC duplication of the gene. The expression of this duplicated gene
CC (At2g07707) is demonstrated.
CC -!- SIMILARITY: Belongs to the ATPase protein YMF19 family. {ECO:0000305}.
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DR EMBL; Y08501; CAA69732.1; -; Genomic_DNA.
DR EMBL; AC007729; AAM15504.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06095.1; -; Genomic_DNA.
DR EMBL; DQ069799; AAY82258.1; -; mRNA.
DR EMBL; BT026104; ABG48460.1; -; mRNA.
DR RefSeq; NP_085508.1; NC_001284.2.
DR RefSeq; NP_178793.1; NM_126751.1.
DR AlphaFoldDB; P93303; -.
DR SMR; P93303; -.
DR BioGRID; 771; 1.
DR IntAct; P93303; 2.
DR STRING; 3702.AT2G07707.1; -.
DR iPTMnet; P93303; -.
DR PaxDb; P93303; -.
DR PRIDE; P93303; -.
DR EnsemblPlants; AT2G07707.1; AT2G07707.1; AT2G07707.
DR EnsemblPlants; ATMG00480.1; ATMG00480.1; ATMG00480.
DR GeneID; 815382; -.
DR Gramene; AT2G07707.1; AT2G07707.1; AT2G07707.
DR Gramene; ATMG00480.1; ATMG00480.1; ATMG00480.
DR KEGG; ath:AT2G07707; -.
DR Araport; AT2G07707; -.
DR Araport; ATMG00480; -.
DR TAIR; locus:2828191; AT2G07707.
DR TAIR; locus:504954531; ATMG00480.
DR eggNOG; ENOG502RXRI; Eukaryota.
DR HOGENOM; CLU_1920741_0_0_1; -.
DR InParanoid; P93303; -.
DR OMA; QWCNAVD; -.
DR OrthoDB; 1310286at2759; -.
DR PhylomeDB; P93303; -.
DR BioCyc; ARA:AT2G07707-MON; -.
DR BioCyc; ARA:ATMG00480-MON; -.
DR PRO; PR:P93303; -.
DR Proteomes; UP000006548; Chromosome 2.
DR Proteomes; UP000006548; Mitochondrion (cv. C24).
DR ExpressionAtlas; P93303; differential.
DR Genevisible; P93303; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005753; C:mitochondrial proton-transporting ATP synthase complex; HDA:TAIR.
DR GO; GO:0000276; C:mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); IDA:TAIR.
DR GO; GO:0005739; C:mitochondrion; IDA:TAIR.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0050897; F:cobalt ion binding; HDA:TAIR.
DR GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:UniProtKB-EC.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:UniProtKB-EC.
DR InterPro; IPR009455; YMF19.
DR InterPro; IPR044975; YMF19-like.
DR InterPro; IPR003319; YMF19-like_N.
DR PANTHER; PTHR36816; PTHR36816; 1.
DR Pfam; PF06449; DUF1082; 1.
DR Pfam; PF02326; YMF19; 1.
PE 1: Evidence at protein level;
KW ATP synthesis; ATP-binding; CF(0); Hydrogen ion transport; Ion transport;
KW Membrane; Mitochondrion; Nucleotide-binding; Reference proteome;
KW Translocase; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..158
FT /note="ATP synthase protein YMF19"
FT /id="PRO_0000196841"
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 158 AA; 18211 MW; B4F1949B09A7B4A9 CRC64;
MPQLDKFTYF SQFFWLCLFF FTFYIFICND GDGVLGISRI LKLRNQLLSH RGKTIRSKDP
NSLEDLLRKG FSTGVSYMYA SLFEVSQWCK AVDLLGKRRK ITLISCFGEI SGSRGMERNI
LYNISKSSPS NTGRWITCRN CRNDIMLIHV VHGQGSIK
