YMK8_YEAST
ID YMK8_YEAST Reviewed; 105 AA.
AC Q03759; D6W0H6;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 03-AUG-2022, entry version 135.
DE RecName: Full=Uncharacterized protein YML108W;
GN OrderedLocusNames=YML108W; ORFNames=YM8339.11;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169872;
RA Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T.,
RA Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K.,
RA Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P.,
RA Skelton J., Walsh S.V., Whitehead S., Barrell B.G.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.";
RL Nature 387:90-93(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [4]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, CLEAVAGE OF INITIATOR
RP METHIONINE [LARGE SCALE ANALYSIS], AND IDENTIFICATION BY MASS SPECTROMETRY
RP [LARGE SCALE ANALYSIS].
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E.,
RA Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-terminal
RT acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
CC -!- MISCELLANEOUS: Present with 2610 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; Z49210; CAA89110.1; -; Genomic_DNA.
DR EMBL; BK006946; DAA09790.1; -; Genomic_DNA.
DR PIR; S53964; S53964.
DR RefSeq; NP_013599.1; NM_001182470.1.
DR PDB; 1N6Z; NMR; -; A=1-105.
DR PDBsum; 1N6Z; -.
DR AlphaFoldDB; Q03759; -.
DR BMRB; Q03759; -.
DR SMR; Q03759; -.
DR BioGRID; 35035; 152.
DR DIP; DIP-3849N; -.
DR IntAct; Q03759; 4.
DR STRING; 4932.YML108W; -.
DR iPTMnet; Q03759; -.
DR MaxQB; Q03759; -.
DR PaxDb; Q03759; -.
DR PRIDE; Q03759; -.
DR DNASU; 854863; -.
DR EnsemblFungi; YML108W_mRNA; YML108W; YML108W.
DR GeneID; 854863; -.
DR KEGG; sce:YML108W; -.
DR SGD; S000004576; YML108W.
DR VEuPathDB; FungiDB:YML108W; -.
DR eggNOG; ENOG502S3ZA; Eukaryota.
DR HOGENOM; CLU_2145549_0_0_1; -.
DR InParanoid; Q03759; -.
DR OMA; HIKYEIT; -.
DR BioCyc; YEAST:G3O-32691-MON; -.
DR EvolutionaryTrace; Q03759; -.
DR PRO; PR:Q03759; -.
DR Proteomes; UP000002311; Chromosome XIII.
DR RNAct; Q03759; protein.
DR GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR GO; GO:0005634; C:nucleus; HDA:SGD.
DR Gene3D; 3.10.20.250; -; 1.
DR InterPro; IPR015080; DUF1892.
DR InterPro; IPR035946; YML108W-like_sf.
DR Pfam; PF08987; DUF1892; 1.
DR SUPFAM; SSF89975; SSF89975; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Acetylation; Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0007744|PubMed:22814378"
FT CHAIN 2..105
FT /note="Uncharacterized protein YML108W"
FT /id="PRO_0000203242"
FT MOD_RES 2
FT /note="N-acetylserine"
FT /evidence="ECO:0007744|PubMed:22814378"
FT STRAND 7..13
FT /evidence="ECO:0007829|PDB:1N6Z"
FT TURN 21..23
FT /evidence="ECO:0007829|PDB:1N6Z"
FT STRAND 25..27
FT /evidence="ECO:0007829|PDB:1N6Z"
FT STRAND 37..43
FT /evidence="ECO:0007829|PDB:1N6Z"
FT HELIX 50..65
FT /evidence="ECO:0007829|PDB:1N6Z"
FT STRAND 72..77
FT /evidence="ECO:0007829|PDB:1N6Z"
FT TURN 78..80
FT /evidence="ECO:0007829|PDB:1N6Z"
FT STRAND 81..86
FT /evidence="ECO:0007829|PDB:1N6Z"
FT HELIX 88..90
FT /evidence="ECO:0007829|PDB:1N6Z"
FT HELIX 91..104
FT /evidence="ECO:0007829|PDB:1N6Z"
SQ SEQUENCE 105 AA; 12339 MW; 8D07986085C369C4 CRC64;
MSKSNTYRML VLLEDDTKIN KEDEKFLKGK PGKMHEFVDE LILPFNVDEL DELNTWFDKF
DAEICIPNEG HIKYEISSDG LIVLMLDKEI EEVVEKVKKF VEENN
