YMPB_CAEEL
ID YMPB_CAEEL Reviewed; 578 AA.
AC Q7Z118; Q10947;
DT 23-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2010, sequence version 2.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Putative transporter B0361.11;
GN ORFNames=B0361.11;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000305}.
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DR EMBL; FO080185; CCD61826.1; -; Genomic_DNA.
DR RefSeq; NP_001021124.2; NM_001025953.3.
DR AlphaFoldDB; Q7Z118; -.
DR SMR; Q7Z118; -.
DR STRING; 6239.B0361.11; -.
DR PaxDb; Q7Z118; -.
DR EnsemblMetazoa; B0361.11.1; B0361.11.1; WBGene00015165.
DR GeneID; 3565709; -.
DR KEGG; cel:CELE_B0361.11; -.
DR UCSC; B0361.11; c. elegans.
DR CTD; 3565709; -.
DR WormBase; B0361.11; CE43666; WBGene00015165; -.
DR eggNOG; KOG0255; Eukaryota.
DR HOGENOM; CLU_001265_33_4_1; -.
DR InParanoid; Q7Z118; -.
DR OMA; IVIWCLV; -.
DR OrthoDB; 704438at2759; -.
DR PhylomeDB; Q7Z118; -.
DR Reactome; R-CEL-112311; Neurotransmitter clearance.
DR Reactome; R-CEL-181430; Norepinephrine Neurotransmitter Release Cycle.
DR Reactome; R-CEL-197264; Nicotinamide salvaging.
DR Reactome; R-CEL-200425; Carnitine metabolism.
DR Reactome; R-CEL-2161517; Abacavir transmembrane transport.
DR Reactome; R-CEL-442660; Na+/Cl- dependent neurotransmitter transporters.
DR Reactome; R-CEL-549127; Organic cation transport.
DR Reactome; R-CEL-561048; Organic anion transport.
DR Reactome; R-CEL-9749641; Aspirin ADME.
DR PRO; PR:Q7Z118; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00015165; Expressed in adult organism and 1 other tissue.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR Pfam; PF00083; Sugar_tr; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Sugar transport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..578
FT /note="Putative transporter B0361.11"
FT /id="PRO_0000050465"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 182..202
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 232..252
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 263..283
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 339..359
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 373..393
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 399..419
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 426..446
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 457..477
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 486..506
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 532..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..30
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 578 AA; 65675 MW; 64FB83EF2AFAEBB4 CRC64;
MSISRRSYEQ FDEMKSENQE NNSKKKSSER LKKLDPDKFV EAYGAYGKYQ IFTYVLVQTL
NFFYSSSMYI MSFVQLNLEK QCEYKNETIP ISETCQIETE SSKAFGNLNG EYCGIAENTL
VNVTNQKAST NLLVDFDLSC SHWFFQEFGL TIFTIGAVIA VPFMSMLADR YGRKPIIVTT
AILAFLANMA ASFSPNFAIF LILRAFIGAC SDSYLSVASV ATCEYLSEKA RAWITVVYNV
AWSLGMVWTL LVTLMTDDWR WRYFIVSLPG VYGFALWYFL PESPHWLITK NKTEKLKKYI
KTANRVNNVS PEFNDCQQSS HHEEKHESFK ALLGSKKLIW LLFANGFIEM VISLVYFAIS
FMSVELGGDQ VQAFLYSSLI EIPAGLAVIP LMMKMGRKMI VIWCLVFQTL ALIGVTVFLD
SYEFKLVIML VAKVMATIIY SVHPIWATEQ FPTSVRSLCF SLMNIPQSMG IIMSPYVKHI
VMSPNWIPFV VIALFSFISA TLAFMLHETK NKKLPTDIES LSYPSETNDL SAYRRSKSSS
SSVSALSKTS VRSKKTLSSE SVSKKLDTVN FSDKEYRI